One-Shot Federated Class-Incremental Learning for Medical Imaging via Variational Feature Transfer

摘要

Federated learning (FL) enables privacy-preserving collaboration for medical image analysis across decentralized institutions but faces major challenges from non-IID data distributions, high communication overhead in multi-round protocols, and catastrophic forgetting when models must adapt to sequentially arriving tasks. These issues are particularly critical in healthcare, where repeated client participation is often infeasible. We address this setting by proposing a novel class-incremental continual learning (CL) model for a one-shot FL paradigm, in which each task introduces new classes, clients observe heterogeneous and evolving class distributions, and communication with the server occurs only once. Clients estimate class-conditional feature distributions via Variational Inference (VI) from private data and transmit compact statistics to the server, which synthesizes features to train a global classifier in a single communication round. The server aggregates these distributional summaries, synthesizes feature embedding, and learns a global classifier without revisiting real past data or contacting clients again. Our major novelty is continual adaptation at the distribution level via synthetic replay from stored class mixtures, complemented by lightweight distillation. This approach substantially mitigates catastrophic forgetting while consistently enhancing recognition of newly introduced classes. Extensive experiments on multiple medical imaging benchmarks demonstrate that our method outperforms both state-of-the-art one-shot FL and class-incremental CL approaches. Compared with existing CL models, it achieves 90–97% average accuracy with near-zero forgetting (≤ 0.10%) across different tasks and evaluation settings.