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Theory · Domain Adaptation and Transfer Learning

Lute Lillo, Nick Cheney

In independent, identically distributed (i.i.d.) training regimes, activation functions have been benchmarked extensively, and their differences often shrink once model size and optimization are tuned. In continual learning, however, the picture is different: beyond catastrophic forgetting, models can progressively lose the ability to adapt—loss of plasticity—and the role of the non-linearity in this failure mode remains underexplored. We show that activation choice is a primary, architecture-agnostic lever for mitigating plasticity loss. Building on a property-level analysis of negative-branch shape and saturation behavior, we introduce two drop-in nonlinearities—Smooth-Leaky and Randomized Smooth-Leaky—and evaluate them in two complementary settings: (i) supervised class-incremental benchmarks and (ii) reinforcement learning with non-stationary MuJoCo environments designed to induce controlled distribution and dynamics shifts. We also provide a simple stress protocol and diagnostics that link the shape of the activation to the adaptation under change. The takeaway is straightforward: thoughtful activation design offers a lightweight, domain-general way to sustain plasticity in continual learning without extra capacity or task-specific tuning.

Deep Learning · Everything Else

JangHyeon Lee, Philipe Dias, Yao-Yi Chiang, Dalton Lunga

Self-supervised learning (SSL) has emerged as a powerful pretraining strategy to learn transferable representations from unlabeled data. Yet, it remains unclear how long SSL models should be pretrained to yield such representations. Contrary to the prevailing heuristic that longer pretraining translates to better downstream performance, we observe a transferability trade-off: across diverse SSL settings, intermediate checkpoints can yield stronger out-of-domain (OOD) generalization, whereas additional pretraining primarily benefits in-domain (ID) performance. From this observation, we hypothesize that SSL progresses through learning phases that can be characterized via the lens of critical periods (CP). Prior work on CP has shown that supervised models exhibit an early phase of high plasticity, followed by a consolidation phase where adaptability declines but task-specific performance increases. Since traditional CP analysis was developed for supervised settings, we rethink it for SSL in two ways. First, we inject deficits to perturb the pretraining data and assess their lasting impact on representation quality via downstream tasks. Second, we compute the Fisher Information on pretext objectives to track plasticity, quantifying how sensitive model parameters are to the pretext task. Our experiments suggest that SSL models may exhibit their own CP, with CP closure coinciding with a sweet spot for broad downstream transferability. Leveraging these insights, we introduce CP-guided checkpoint selection as a strategy for selecting checkpoints that offer stronger OOD transferability. Finally, to balance the transferability trade-off, we present CP-guided self-distillation, which selectively distills layer representations from the intermediate checkpoint into their overspecialized counterparts in the final checkpoint.

Theory · Domain Adaptation and Transfer Learning

Xiao MA, Young D. Kwon, Pan Zhou, Dong Ma

Test-Time Adaptation (TTA) adapts a deployed model during online inference to mitigate the impact of domain shift. While achieving strong accuracy, most existing methods rely on backpropagation, which is memory and computation intensive, making them unsuitable for resource-constrained devices. Recent attempts to reduce this overhead often suffer from high latency or are tied to specific architectures such as ViT-only or CNN-only. In this work, we revisit domain shift from an embedding perspective. Our analysis reveals that domain shift induces three distinct structural changes in the embedding space: translation (mean shift), scaling (variance shift), and rotation (covariance shift). Based on this insight, we propose Progressive Embedding Alignment (PEA), a backpropagation-free and architecture-agnostic TTA approach. By applying a novel covariance alignment procedure at each intermediate layer, PEA efficiently corrects the embedding distortions with only two forward passes. Extensive experiments demonstrate that PEA achieves state-of-the-art performance in both accuracy and efficiency, while also proving versatile across different architectures including ViTs and CNNs.

Theory · Domain Adaptation and Transfer Learning

Guohao Chen, Shuaicheng Niu, Chen Deyu, Jiahao Yang, Zitian Zhang, Mingkui Tan, Pengcheng Wu, Zhiqi Shen

Test-time entropy minimization helps adapt a model to novel environments and incentivize its reasoning capability, unleashing the model's potential during inference by allowing it to evolve and improve in real-time using its own predictions, achieving promising performance. However, pure entropy minimization can favor non-generalizable shortcuts, such as inflating the logit norm and driving all predictions to a dominant class to reduce entropy, risking collapsed solutions (e.g., constant one-hot outputs) that trivially minimize the objective without meaningful learning. In this paper, we reveal asymmetry as a key mechanism for collapse prevention and introduce ZeroSiam--an efficient asymmetric Siamese architecture tailored for test-time entropy minimization. ZeroSiam prevents collapse through asymmetric divergence alignment, efficiently achieved by a learnable predictor and a stop-gradient operator before the classifier. We provide empirical and theoretical evidence that ZeroSiam not only prevents collapse, but also regularizes biased learning signals, enhancing performance even when no collapse occurs. Despite its simplicity, extensive results show that ZeroSiam performs more stably over prior methods using negligible overhead, demonstrating efficacy on both vision adaptation and large language model reasoning tasks across challenging test scenarios and diverse models, including particularly collapse-prone tiny models.

Theory · Domain Adaptation and Transfer Learning

Raphaella Diniz, Jackson de Faria, Martin Ester

The goal of domain adaptation is to make predictions for unlabeled samples from a target domain with the help of labeled samples from a different but related source domain. The performance of domain adaptation methods is highly influenced by the choice of source domain and pre-trained feature extractor. However, the selection of source data and pre-trained model is not trivial due to the absence of a labeled validation set for the target domain and the large number of available pre-trained models. In this work, we propose PAS, a novel score designed to estimate the transferability of a source domain set and a pre-trained feature extractor to a target classification task before actually performing domain adaptation. PAS leverages the generalization power of pre-trained models and assesses source-target compatibility based on the pre-trained feature embeddings. We integrate PAS into a framework that indicates the most relevant pre-trained model and source domain among multiple candidates, thus improving target accuracy while reducing the computational overhead. Extensive experiments on image classification benchmarks demonstrate that PAS correlates strongly with actual target accuracy and consistently guides the selection of the best-performing pre-trained model and source domain for adaptation.

Reinforcement Learning · Deep RL

Ming-Hong Chen, Kuan-Chen Pan, You-De Huang, Xi Liu, Ping-Chun Hsieh

Cross-domain reinforcement learning (CDRL) is meant to improve the data efficiency of RL by leveraging the data samples collected from a source domain to facilitate the learning in a similar target domain. Despite its potential, cross-domain transfer in RL is known to have two fundamental and intertwined challenges: (i) The source and target domains can have distinct state space or action space, and this makes direct transfer infeasible and thereby requires more sophisticated inter-domain mappings; (ii) The transferability of a source-domain model in RL is not easily identifiable a priori, and hence CDRL can be prone to negative effect during transfer. In this paper, we propose to jointly tackle these two challenges through the lens of \textit{cross-domain Bellman consistency} and \textit{hybrid critic}. Specifically, we first introduce the notion of cross-domain Bellman consistency as a way to measure transferability of a source-domain model. Then, we propose $Q$Avatar, which combines the Q functions from both the source and target domains with an adaptive hyperparameter-free weight function. Through this design, we characterize the convergence behavior of $Q$Avatar and show that $Q$Avatar achieves reliable transfer in the sense that it effectively leverages a source-domain Q function for knowledge transfer to the target domain. Through experiments, we demonstrate that $Q$Avatar achieves favorable transferability across various RL benchmark tasks, including locomotion and robot arm manipulation. Our code is available at https://rl-bandits-lab.github.io/Cross-Domain-RL/.

General Machine Learning · Transfer, Multitask and Meta-learning

Rundong He, Jieming Shi

Deep neural networks (DNNs) have been effectively deployed in tabular data modeling for various applications. However, these models suffer severe performance degradation when distribution shifts exist between training and test tabular data. While test-time adaptation (TTA) serves as a promising solution to distribution shifts, existing TTA methods primarily focus on visual modalities and demonstrate poor adaptation when directly applied to tabular modality. Recent efforts have proposed tabular-specific TTA approaches to mitigate distribution shifts on tabular data. Nevertheless, these methods inherently assume the accessibility of source domain or prior and fail to fundamentally address feature shift while overlooking unique characteristics of tabular data, leading to suboptimal adaptation. In this paper, we focus on the problem of \textit{prior-free tabular test-time adaptation} where no access to source data and any prior knowledge is allowed, and we propose a novel method, \underline{P}rior-\underline{F}ree \underline{T}abular \underline{T}est-\underline{T}ime \underline{A}daptation (PFT$_3$A), which has three designs to simultaneously address label shift and feature shift without source domain or prior access. Specially, PFT$_3$A contains the \textit{Class Prior Estimating} module for estimating source-target class priors to calibrate prediction, eliminating dependency on source class prior and mitigating label shift; the \textit{Robust Feature Learning} module for learning robust feature by aligning source-like and target-like features to mitigate feature shift; the \textit{Representative Subspace Exploration} module for eliminating redundant features by projecting feature into subspace to enhance feature alignment. Extensive experiments demonstrate the effectiveness and generalization of PFT$_3$A in tabular TTA tasks. The implementation is at \url{https://github.com/rundohe/PFT3A}.

Applications · Chemistry and Drug Discovery

Gen Zhou, Sugitha Janarthanan, Lianghong Chen, Pingzhao Hu

To address the global health threat of antimicrobial resistance, antimicrobial peptides (AMP) are being explored for their potent and promising ability to fight resistant pathogens. While artificial intelligence (AI) is being employed to advance AMP discovery and design, most AMP design models struggle to balance key goals like activity, toxicity, and novelty, using rigid or unclear scoring methods that make results hard to interpret and optimize. As the capabilities of Large Language Models (LLM) advance and evolve swiftly, we turn to AI multi-agent collaboration based on such models (multi-agent LLMs), which show rapidly rising potential in complex scientific design scenarios. Based on this, we introduce $\textbf{MAC-AMP}$, a closed-loop multi-agent collaboration (MAC) system for multi-objective AMP design. The system implements a fully autonomous simulated peer review-adaptive reinforcement learning framework that requires only a task description and example dataset to design novel AMPs. The novelty of our work lies in introducing a closed-loop multi-agent system for AMP design, with cross-domain transferability, that supports multi-objective optimization while remaining explainable rather than a 'black box'. Experiments show that MAC-AMP outperforms other AMP generative models by effectively optimizing AMP generation for multiple key molecular properties, demonstrating exceptional results in antibacterial activity, AMP likeliness, toxicity compliance, and structural reliability.

Social Aspects · Accountability, Transparency and Interpretability

Qi Zhang, Yifei Wang, Xiaohan Wang, Jiajun Chai, Guojun Yin, Wei Lin, Yisen Wang

In recent years, pre-trained large language models have achieved remarkable success across diverse tasks. Besides the pivotal role of self-supervised pre-training, their effectiveness in downstream applications also depends critically on the post-training process, which adapts models to task-specific data and objectives. However, this process inevitably introduces model shifts that can influence performance in different domains, and how such shifts transfer remains poorly understood. To open up the black box, we propose the SAE-based Transferability Score (STS), a new metric that leverages sparse autoencoders (SAEs) to forecast post-training transferability. Taking supervised fine-tuning as an example, STS identifies shifted dimensions in SAE representations and calculates their correlations with downstream domains, enabling reliable estimation of transferability \textit{before} fine-tuning. Extensive experiments across multiple models and domains show that STS accurately predicts the transferability of supervised fine-tuning, achieving Pearson correlation coefficients above 0.7 with actual performance changes. Beyond this, we take an initial step toward extending STS to reinforcement learning. We believe that STS can serve as an {\color{black} interpretable} tool for guiding post-training strategies in LLMs. Code is available at \url{https://github.com/PKU-ML/STS}.

Applications · Chemistry and Drug Discovery

Yuanpeng Zhang, Zhijian Huang, Ziyu Fan, Siyuan Shen, Yahan Li, Shangqian Wu, Min Wu, Lei Deng

Cancer treatment efficacy exhibits high inter-patient heterogeneity due to genomic variations. While large-scale in vitro drug response data from cancer cell lines exist, predicting patient drug responses remains challenging due to genomic distribution shifts and the scarcity of clinical response data. Existing transfer learning methods primarily align global genomic features between cell lines and patients. However, they often ignore two critical aspects. First, drug response depends on specific drug substructures and genomic pathways. Second, drug response mechanisms differ in vitro and in vivo settings due to factors such as the immune system and tumor microenvironment. To address these limitations, we propose DeepSADR, a novel deep transfer learning framework for enhanced drug response prediction based on subsequence interaction and adaptive readout. In particular, DeepSADR models drug responses as interpretable bipartite interaction graphs between drug substructures and enriched genomic pathways. Subsequently, a supervised graph autoencoder was designed to capture latent interactions between drugs and gene subsequences within these interaction graphs. In addition, DeepSADR treats the drug response process as a transferable domain. A Set Transformer-based adaptive readout (AR) function learns domain-invariant response representations, enabling effective knowledge transfer from abundant cell line data to scarce patient data. Extensive experiments on clinical patient cohorts demonstrate that DeepSADR significantly outperforms state-of-the-art methods, and ablation experiments have validated the effectiveness of each module.

Theory · Domain Adaptation and Transfer Learning

Sunghyun Baek, Jaemyung Yu, Seunghee Koh, Minsu Kim, Hyeonseong Jeon, Junmo Kim

Test-time adaptation (TTA) has been widely explored to prevent performance degradation when test data differ from the training distribution. However, fully leveraging the rich representations of large pretrained models with minimal parameter updates remains underexplored. In this paper, we propose Intrinsic Mixture of Spectral Experts (IMSE) that leverages the spectral experts inherently embedded in Vision Transformers. We decompose each linear layer via singular value decomposition (SVD) and adapt only the singular values, while keeping the singular vectors fixed. We further identify a key limitation of entropy minimization in TTA: it often induces feature-collapse, causing the model to rely on domain-specific features rather than class-discriminative features. To address this, we propose a diversity maximization loss based on expert–input alignment, which encourages diverse utilization of spectral experts during adaptation. In the continual test-time adaptation (CTTA) scenario, beyond preserving pretrained knowledge, it is crucial to retain and reuse knowledge from previously observed domains. We introduce Domain-Aware Spectral Code Retrieval, which estimates input distributions to detect domain shifts, and retrieves adapted singular values for rapid adaptation. Consequently, our method achieves state-of-the-art performance on various distribution-shift benchmarks under the TTA setting. In CTTA and Gradual CTTA, it further improves accuracy by 3.4 percentage point (pp) and 2.4 pp, respectively, while requiring 385 times fewer trainable parameters. Our code is available in https://github.com/baek85/IMSE.

Theory · Domain Adaptation and Transfer Learning

Neil Marchant, Andrew Cullen, Feng Liu, Sarah Erfani

Deep neural networks often fail when deployed in real-world contexts due to distribution shift, a critical barrier to building safe and reliable systems. An emerging approach to address this problem relies on _disagreement discrepancy_—a measure of how the disagreement between two models changes under a shifting distribution. The process of maximizing this measure has seen applications in bounding error under shifts, testing for harmful shifts, and training more robust models. However, this optimization involves the non-differentiable zero-one loss, necessitating the use of practical surrogate losses. We prove that existing surrogates for disagreement discrepancy are not Bayes consistent, revealing a fundamental flaw: maximizing these surrogates can fail to maximize the true disagreement discrepancy. To address this, we introduce new theoretical results providing both upper and lower bounds on the optimality gap for such surrogates. Guided by this theory, we propose a novel disagreement loss that, when paired with cross-entropy, yields a provably consistent surrogate for disagreement discrepancy. Empirical evaluations across diverse benchmarks demonstrate that our method provides more accurate and robust estimates of disagreement discrepancy than existing approaches, particularly under challenging adversarial conditions.

Theory · Domain Adaptation and Transfer Learning

Seonghwi Kim, Sungho Jo, Wooseok Ha, Minwoo Chae

Unsupervised domain adaptation (UDA) is a statistical learning problem when the distribution of training (source) data is different from that of test (target) data. In this setting, one has access to labeled data only from the source domain and unlabeled data from the target domain. The central objective is to leverage the source data and the unlabeled target data to build models that generalize to the target domain. Despite its potential, existing UDA approaches often struggle in practice, particularly in scenarios where the target domain offers only limited unlabeled data or spurious correlations dominate the source domain. To address these challenges, we propose a novel distributionally robust learning framework that models uncertainty in both the covariate distribution and the conditional label distribution. Our approach is motivated by the multi-source domain adaptation setting but is also directly applicable to the single-source scenario, making it versatile in practice. We develop an efficient learning algorithm that can be seamlessly integrated with existing UDA methods. Extensive experiments under various distribution shift scenarios show that our method consistently outperforms strong baselines, especially when target data are extremely scarce.

Theory · Domain Adaptation and Transfer Learning

Parham Rezaei, Filip Kovačević, Francesco Locatello, Marco Mondelli

Despite the progress in the development of generative models, their usefulness in creating synthetic data that improve prediction performance of classifiers has been put into question. Besides heuristic principles such as ''synthetic data should be close to the real data distribution'', it is actually not clear which specific properties affect the generalization error. Our paper addresses this question through the lens of high-dimensional regression. Theoretically, we show that, for linear models, the *covariance shift* between the target distribution and the distribution of the synthetic data affects the generalization error but, surprisingly, the mean shift does not. Furthermore, in some regimes, we prove that matching the covariance of the target distribution is optimal. Remarkably, the theoretical insights for linear models carry over to deep neural networks and generative models. We empirically demonstrate that the *covariance matching* procedure (matching the covariance of the synthetic data with that of the data coming from the target distribution) performs well against several recent approaches for synthetic data selection, across various training paradigms, datasets and generative models used for augmentation.

Theory · Domain Adaptation and Transfer Learning

Ziquan Zhu, Hanruo Zhu, Si-Yuan Lu, Xiang Li, Yanda Meng, Yunxiao Zhang, Gaojie Jin, Lu Yin, Lijie Hu, Di Wang 等

Adapters have become a widely adopted strategy for efficient fine-tuning of foundation models, particularly in resource-constrained settings. However, their performance under extreme data scarcity—common in medical imaging due to high annotation costs, privacy regulations, and fragmented datasets—remains underexplored. In this work, we present the first comprehensive study of adapter-based fine-tuning for vision foundation models in low-data medical imaging scenarios. We find that, contrary to their promise, conventional Adapters can degrade performance under severe data constraints, performing even worse than simple linear probing when trained on less than 1\% of the corresponding training data. Through systematic analysis, we identify a sharp reduction in Effective Receptive Field (ERF) as a key factor behind this degradation. Motivated by these findings, we propose the Dual-Kernel Adapter (DKA), a lightweight module that expands spatial context via large-kernel convolutions while preserving local detail with small-kernel counterparts. Extensive experiments across diverse classification and segmentation benchmarks show that DKA significantly outperforms existing Adapter methods, establishing new leading results in both data-constrained and data-rich regimes.

Theory · Domain Adaptation and Transfer Learning

Yichen Xu, Ryumei Nakada, Linjun Zhang, Lexin Li

Transfer learning has become a central paradigm in modern machine learning, yet it suffers from the long-standing problem of negative transfer, where leveraging source representations can harm rather than help performance on the target task. Although empirical remedies have been proposed, there remains little theoretical understanding of how to reliably avoid negative transfer. In this paper, we investigate a simple yet remarkably effective strategy: augmenting frozen, pretrained source-side features with a trainable target-side encoder that adapts target features to capture residual signals overlooked by models pretrained on the source data. We show this residual feature integration strategy is sufficient to provably prevent negative transfer, by establishing theoretical guarantees that it has no worse convergence rate than training from scratch under the informative class of target distributions up to logarithmic factors, and that the convergence rate can transition seamlessly from nonparametric to near-parametric when source representations are informative. To our knowledge, this is the first theoretical work that ensures protection against negative transfer. We carry out extensive numerical experiments across image, text and tabular benchmarks, and empirically verify that the method consistently safeguards performance under distribution shift, label noise, semantic perturbation, and class imbalance. We additionally demonstrate that this residual integration mechanism uniquely supports adapt-time multimodality extension, enabling a pretrained single-cell foundation model to incorporate spatial signals for lymph-node anatomical classification despite the source model being trained without them. Our study thus advances the theory of safe transfer learning, and provides a principled approach that is simple, robust, architecture-agnostic, and broadly applicable.

Deep Learning · Graph Neural Networks

Rishabh Ranjan, Valter Hudovernik, Mark Znidar, Charilaos Kanatsoulis, Roshan Upendra, Mahmoud Mohammadi, Joe Meyer, Tom Palczewski, Carlos Guestrin, Jure Leskovec

Pretrained transformers readily adapt to new sequence modeling tasks via zero-shot prompting, but relational domains still lack architectures that transfer across datasets and tasks. The core challenge is the diversity of relational data, with varying heterogeneous schemas, graph structures and functional dependencies. In this paper, we present the Relational Transformer (RT) architecture, which can be pretrained on diverse relational databases and directly applied to unseen datasets and tasks without task- or dataset-specific fine-tuning, or retrieval of in-context examples. RT (i) incorporates task specification via task table prompting, (ii) tokenizes cells with table/column metadata, (iii) is pretrained via masked token prediction, and (iv) utilizes a novel Relational Attention mechanism over columns, rows, and primary-foreign key links. Pretrained on RelBench datasets spanning tasks such as churn and sales forecasting, RT attains strong zero-shot performance, averaging 93% of fully supervised AUROC on binary classification tasks with a single forward pass of a 22M parameter model, as opposed to 84% for a 27B LLM. Fine-tuning yields state-of-the-art results with high sample efficiency. Our experimental analyses show that RT's zero-shot transfer leverages task context, relational attention patterns and schema semantics. Overall, RT provides a practical path toward foundation models for relational data. Code, models, data: https://github.com/snap-stanford/relational-transformer.

Theory · Domain Adaptation and Transfer Learning

Heayoun Choi, Hyundong Jin, Eunwoo Kim

Class-Incremental Learning (CIL) traditionally assumes that all tasks share a similar domain distribution, limiting its applicability in real-world scenarios where data arrive from evolving environments. We introduce a new problem setting, Cross-Expanding Incremental Learning (XIL), which extends CIL by requiring models to handle class-incremental data across distinct domains and to expand class-domain associations bidirectionally. In this setting, new classes should be integrated into previously seen domains, while earlier classes are extended to newly encountered ones, a capability we refer to as bidirectional domain transferability (BiDoT). To address XIL, we present a new framework, Semantic Expansion through Evolving Domains (XEED), which leverages domain-specialized prompts, residual-guided representation modulation, and evolving prototype embeddings to expand class semantics across previously encountered domains. We further introduce the BiDoT Score, a novel metric for quantifying the degree of BiDoT. Extensive experiments on benchmark datasets with significant domain shifts demonstrate that XEED outperforms existing CIL baselines by a large margin in both standard accuracy and BiDoT scores, establishing a strong foundation for realistic continual learning under domain-evolving conditions.

Theory · Domain Adaptation and Transfer Learning

ChanJoo Jung, Jaehyung Kim

Large Language Models (LLMs) are widely applied in real world scenarios, yet fine-tuning them comes with significant computational and storage costs. Parameter-Efficient Fine-Tuning (PEFT) methods such as LoRA mitigate these costs; however, the adapted parameters are dependent on the base model and cannot be transferred across different backbones. One way to address this issue is through knowledge distillation, but its effectiveness inherently depends on training data. Recent work such as TransLoRA avoids this by generating synthetic data; nevertheless, this adds complexity since it requires training an additional discriminator model. In this paper, we propose TiTok, a new framework that enables effective LoRA Transplantation through Token-level knowledge transfer. Specifically, TiTok captures task-relevant information through a token-wise contrastive excess between a source model with and without LoRA. This excess highlights informative tokens and enables selective filtering of synthetic data, all without additional models or overhead. Through experiments on three benchmarks across multiple transfer settings, we demonstrate that TiTok is consistently effective, achieving average performance gains of +4–10% compared to baselines overall.

Theory · Domain Adaptation and Transfer Learning

Boyang Dai, 曾 Fan, Zihao Qi, Meng Lou, Yizhou Yu

Source-Free Domain Adaptive Object Detection (SF-DAOD) aims to adapt a detector trained on a labeled source domain to an unlabeled target domain without retaining any source data. Despite recent progress, most popular approaches focus on tuning pseudo-label thresholds or refining the teacher-student framework, while overlooking object-level structural cues within cross-domain data. In this work, we present CGSA, the first framework that brings Object-Centric Learning (OCL) into SF-DAOD by integrating slot-aware adaptation into the DETR-based detector. Specifically, our approach integrates a Hierarchical Slot Awareness (HSA) module into the detector to progressively disentangle images into slot representations that act as visual priors. These slots are then guided toward class semantics via a Class-Guided Slot Contrast (CGSC) module, maintaining semantic consistency and prompting domain-invariant adaptation. Extensive experiments on multiple cross-domain datasets demonstrate that our approach outperforms previous SF-DAOD methods, with theoretical derivations and experimental analysis further demonstrating the effectiveness of the proposed components and the framework, thereby indicating the promise of object-centric design in privacy-sensitive adaptation scenarios. Code is released at https://github.com/Michael-McQueen/CGSA.