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Bingxian Wu, Yu Zhang, Zonghao Guo, Tang Liu, Chen Qian, Yuxiang Lu, Xingbo Du, Yanghao Li, Yidan Zhang, Chi Chen 等

Geoscience research requires complex analysis and domain expertise, with remote sensing (RS) observations as a key foundation. However, existing RS agents built on general-purpose LLMs remain largely domain-agnostic, resulting in brittle and error-prone workflows. Moreover, these failures are seldom consolidated into a reusable experience for subsequent analyses. To address this issue, we introduce RSMeM, a knowledge-enhanced memory evolution mechanism that bootstraps RS agents with pre-distilled domain knowledge and iteratively integrates online experience for robust multi-step tool execution. RSMeM is composed of two components: (i) Hierarchical Knowledge Grounding, which performs taxonomy-aware retrieval over a hierarchical domain corpus to guide planning and tool selection; and (ii) Failure-Aware Experience Refinement, which distills failure-annotated tool-use traces into reusable constraints for next-round tool execution. By iteratively employing these two processes, RS agents can evolve to absorb task-level domain knowledge and effectively translate it into instance-level execution experience. Extensive experiments on EarthBench demonstrate that RSMeM consistently improves tool-use performance and end-to-end accuracy across a diverse set of LLM backbones. Notably, RSMeM achieves a 6% accuracy improvement on DeepSeek-V3.2 with less than 1% additional experience tokens, demonstrating the knowledge density of our distilled experience. All codes and models will be released to support reproducible research.

Yucheng Zhou, Dubing Chen, Huan Zheng, Jianbing Shen

Recent advances in text-to-image (T2I) generation have enabled visually coherent image synthesis from descriptions, but generating images containing multiple given subjects remains challenging. As the number of reference identities increases, existing methods often suffer from subject missing and semantic drift. To address this problem, we propose MUSIC, the first MLLM specifically designed for MUlti-Subject In-Context image generation. To overcome the data scarcity, we introduce an automatic and scalable data generation pipeline that eliminates the need for manual annotation. Furthermore, we enhance the model’s understanding of multi-subject semantic relationships through a vision chain-of-thought (CoT) mechanism, guiding step-by-step reasoning from subject images to semantics and generation. To mitigate identity entanglement and manage visual complexity, we develop a novel semantics-driven spatial layout planning method and demonstrate its test-time scalability. By incorporating complex subject images during training, we improve the model’s capacity for chained reasoning. In addition, we curate MSIC, a new benchmark tailored for multi-subject in-context generation. Experimental results demonstrate that MUSIC significantly surpasses other methods in both multi- and single-subject scenarios.

Haohua Song, Wenhao Gu, Zhijing Li, Yunwenyu, Tiantian Zhu, Xiao Yang, Zexuan Zhu

Biomedical document-level relation extraction poses significant challenges beyond sentence-level tasks, as it necessitates the integration of evidence from entire documents and the ability for coherent cross-sentence reasoning. While pretrained language models (PLMs) demonstrate efficiency in handling local contexts, they often struggle with global dependency modeling. Conversely, large language models (LLMs) exhibit strong reasoning capabilities but tend to generate hallucinations in knowledge-intensive biomedical domains. This paper introduces CoRE, a novel cascade framework that leverages the complementary strengths of PLMs and LLMs through a detect-then-rethink paradigm. The PLM serves as an efficient detector for high-confidence relations, while challenging cases are forwarded to an LLM enhanced with semantic retrieval and iterative reasoning mechanisms. Experimental results on BioRED and CDR datasets show that CoRE achieves substantial improvements over state-of-the-art baselines, validating the effectiveness of the proposed cascade paradigm for complex biomedical relation extraction.

Zekai Lin, Chao Xue, Di Liang, Xingsheng Han, Peiyang Liu, Xianjie Wu, Lei Jiang, Yu Lu, Bob Simons, Shuang Liang 等

Supervised Fine-Tuning (SFT) of large language models often suffers from task interference and catastrophic forgetting. Recent approaches alleviate this issue by isolating task-critical parameters during training. However, these methods represent a static solution to a dynamic problem, assuming that parameter importance remains fixed once identified. In this work, we empirically demonstrate that parameter importance exhibits temporal drift over the course of training. To address this, we propose Evolving Parameter Isolation (EPI), a fine-tuning framework that adapts isolation decisions based on online estimates of parameter importance. Instead of freezing a fixed subset of parameters, EPI periodically updates isolation masks using gradient-based signals, enabling the model to protect emerging task-critical parameters while releasing outdated ones to recover plasticity. Experiments on diverse multi-task benchmarks demonstrate that EPI consistently reduces interference and forgetting compared to static isolation and standard fine-tuning, while improving overall generalization. Our analysis highlights the necessity of synchronizing isolation mechanisms with the evolving dynamics of learning diverse abilities.

Kai Wei, Yuwen Cui, Kehan Shen, Hua Wei, Guangjing Wang

Terminal simulation, framed as a terminal command-level Turing test, is a long-standing problem of symbolic language generation in dialogue and interactive systems. Prior scripted simulators lack the flexibility needed for complex, multi-turn interactions, while LLM-based approaches often misinterpret commands, break output formats, drift from system state, and remain vulnerable to prompt injection. In this work, we propose MANTIS, a terminal simulation framework that improves realism, consistency, and robustness in command-language generation. MANTIS integrates a multi-agent architecture with a filter-based routing model that safely dispatches commands to external tools or an LLM-based agent, enabling support for interactive commands while defending against prompt injection attacks. In addition, we design an agentic file system with history pruning to preserve long-term state consistency. We release three datasets: 28,045 real terminal input-output pairs, a 1,000-session multi-turn interaction dataset, and a 25,849-instance labeled classification dataset. MANTIS outperforms state-of-the-art baselines by more than 9%, achieving over 95% accuracy on multi-turn terminal simulation. The dataset and source code are available at https://github.com/kaiwei666a/MANTIS_Terminal_Simulation

Yoonji Kim, Jieun Kim, Yujin Jeong, Sung-Bae Cho

Consistent reasoning about 3D spatial relations across changing viewpoints is fundamental for Embodied AI agents operating in dynamic environments. While Large Vision-Language Models (LVLMs) have advanced multimodal perception, their ability to maintain spatial consistency across diverse perspectives remains underexplored. Existing benchmarks primarily assess spatial capabilities from a static, single-view, and egocentric perspective, failing to capture the dynamic nature of real-world spatial cognition.To address this gap, we introduce SCOPE (Spatial COnsistency across PErspectives and Viewpoints), a comprehensive benchmark designed to rigorously diagnose spatial reasoning capabilities. Grounded in human cognitive theories of dual spatial representations, SCOPE discretizes the 360^\circ field into multiview scenarios to systematically evaluate both allocentric and egocentric reasoning capabilities. Our dataset comprises 20.1K spatial VQA pairs derived from high-quality 3D environments. Through an extensive evaluation of 26 state-of-the-art LVLMs, we identify two fundamental limitations that prevent consistent spatial understanding across viewpoints.We hope SCOPE facilitates the diagnosis of spatial reasoning, serving as a stepping stone toward reliable embodied action.

Ming Li, Chenrui Fan, Yize Cheng, Soheil Feizi, Tianyi Zhou

Large language models increasingly expose reasoning traces, yet their underlying cognitive structure and steps remain difficult to identify and analyze beyond surface-level statistics. We adopt Schoenfeld’s Episode Theory as an inductive, intermediate-scale lens and introduce ThinkARM (Anatomy of Reasoning in Models), a scalable framework that explicitly abstracts reasoning traces into functional reasoning steps such as Analysis, Explore, Implement, Verify, etc. When applied to mathematical problem solving by diverse models, this abstraction reveals reproducible thinking dynamics and structural differences between reasoning and non-reasoning models, which are not apparent from token-level views. We further present two diagnostic case studies showing that exploration functions as a critical branching step associated with correctness, and that efficiency-oriented methods selectively suppress evaluative feedback steps rather than uniformly shortening responses. Together, our results demonstrate that episode-level representations make reasoning steps explicit, enabling systematic analysis of how reasoning is structured, stabilized, and altered in modern language models.

Daniel Zhang-Li, Joy Jia Yin Lim, Binglin Liu, Shangqing Tu, Zijun Yao, Hao Peng, Jifan Yu, Haoxuan Li, Zhanxin Hao, Ye He 等

Project-Based Learning (PBL) is an important learning method that promotes understanding and acquiring practical skills through training learners through a project. However, effective PBL often requires sustained orchestration and collaboration, but existing LLM-based learning tools provide partial assistance without explicitly modeling these roles, and overly comprehensive help provided by LLM can reduce learner autonomy. We propose SimPBL, a multi-agent framework with an orchestrator agent that provides adaptive scaffolding from interaction logs and collaborator agents that support project work through boundary-aware collaboration. We conduct comprehensive evaluation to study the effectiveness of SimPBL, where we observe a 14% improvement in learner examination score. Results from extensive studies further highlights the ability of SimPBL to manage learning behavior and improve learning experience. Code and materials are available at https://anonymous.4open.science/r/SimPBL-D5B8.

Yangyi Li, Chenxu Zhao, Mengdi Huai

Large Reasoning Models (LRMs) have recently demonstrated significant improvements in complex reasoning. While quantifying generation uncertainty in LRMs is crucial, traditional methods are often insufficient because they do not provide finite-sample guarantees for reasoning-answer generation. Conformal prediction (CP) stands out as a model-agnostic methodology that constructs statistically rigorous uncertainty sets. However, existing CP methods ignore the logical connection between the reasoning trace and the final answer. Additionally, prior studies fail to interpret the origins of uncertainty coverage for LRMs as they typically overlook the specific training factors driving valid reasoning. Notably, it is challenging to disentangle reasoning quality from answer correctness, while simultaneously establishing theoretical guarantees for computationally efficient explanation methods. To address these challenges, we first propose a novel methodology that provides the uncertainty of the reasoning-answer structure with statistical guarantees. Subsequently, we develop a unified example-to-step explanation framework using Shapley values that identifies a provably sufficient subset of training data and their specific reasoning steps sufficient to achieve coverage. We also provide the theoretical analysis for our proposed methods. Extensive experiments on challenging reasoning datasets verify the effectiveness of the proposed methods.

Jonas Mayer Martins, Jaap Jumelet, Viola Priesemann, Lisa Beinborn

Why do some languages like Czech permit free word order, while others like English do not? We address this question by pretraining transformer language models on a spectrum of synthetic word-order variants of natural languages. We observe that greater word-order irregularity consistently raises model surprisal, indicating reduced learnability. Sentence reversal, however, affects learnability only weakly. A coarse distinction of free- (e.g., Czech and Finnish) and fixed-word-order languages (e.g., English and French) does not explain cross-lingual variation. Instead, the structure of the word and subword vocabulary strongly predicts the model surprisal. Overall, vocabulary structure emerges as a key driver of computational word-order learnability across languages.

Quoc Phong Dao, Hoang Son Nguyen, Pham Khanh Chi, Linh Ngo Van, Nguyen Thi Ngoc Diep, Thien Huu Nguyen, Trung Le

Knowledge Distillation (KD) has established itself as a pivotal technique for compressing large pre-trained language models. However, existing methods that force a student to strictly mimic the teacher’s sentence embeddings or internal features often incur prohibitive computational costs and yield suboptimal performance due to the inherent capacity gap. To address these challenges, we propose TALAS (Teacher-Anchored Layer Alignment with Sharpness-aware minimization), a unified framework that synergizes hierarchical (multi-layer) alignment with robust optimization. First, we introduce a Teacher-Anchored mechanism that selectively distills final sentence embeddings only into the student’s upper layers, thereby reducing overhead while respecting capacity constraints. Second, we bridge the semantic gap in lower layers via Layer-Aligned Self-Distillation, which propagates knowledge top-down using internal geometric relational constraints in the embedding space. Finally, to prevent the student from memorizing point-wise teacher noise, we integrate Adaptive Sharpness-Aware Minimization (ASAM) into the training objective, guiding the model towards flat minima for enhanced generalization. Empirical results on standard sentence embedding benchmarks demonstrate that TALAS consistently outperforms strong distillation baselines while achieving superior training efficiency in terms of computational cost and memory footprint.

Parker Seegmiller, Sarah Masud Preum

LLMs are increasingly deployed in dynamic, real-world settings, where the distribution of user prompts can shift substantially over time as new tasks, prompts, and users are introduced to a deployed model. Such natural prompt distribution shift poses a major challenge to LLM reliability, particularly for specialized models designed for narrow domains or user populations. Despite attention to out-of-distribution robustness, there is very limited exploration of measuring natural prompt distribution shift in prior work, and its impact on deployed LLMs remains poorly understood. We introduce the LLM Evaluation under Natural prompt Shift (LENS) framework: a data-centric approach for quantifying natural prompt distribution shift and evaluating its effect on the performance of deployed LLMs. We perform a large-scale evaluation using 192 real-world post-deployment prompt shift settings over time, user group, and geographic axes, training a total of 81 models on 4.68M training prompts, and evaluating on 57.6k prompts. We find that even moderate shifts in user prompt behavior correspond with large performance drops (73% average loss) in deployed LLMs. This performance degradation is particularly prevalent when users from different latent groups and geographic regions interact with models and is correlated with natural prompt distribution shift over time. We systematically characterize how LLM instruction following ability degrades over time and between user groups. Our findings highlight the critical need for data-driven monitoring to ensure LLM performance remains stable across diverse and evolving user populations.

Pham Khanh Chi, Quoc Phong Dao, Thuat Nguyen, Linh Ngo Van, Trung Le, Thanh Hong Nguyen

Knowledge distillation is a key technique for compressing large language models (LLMs), but most existing methods align representations at fixed layers or token-level outputs, ignoring how representations evolve across depth. As a result, the student is only weakly guided to capture the teacher’s internal relational structure during distillation, which limits knowledge transfer. To address this limitation, we propose Multi-Granular Trajectory Alignment (MTA), a framework that aligns teacher and student representations along their layer-wise transformation trajectory. MTA adopts a layer-adaptive strategy: lower layers are aligned at the word level to preserve lexical information, while higher layers operate on phrase-level spans (e.g., noun and verb phrases) to capture compositional semantics. We instantiate this idea through a Dynamic Structural Alignment loss that matches the relative geometry among semantic units within each layer. This design is motivated by empirical findings that Transformer representations become increasingly abstract with depth, and is also consistent with linguistic views in which higher-level meaning emerges through the composition of lower-level lexical units. We further incorporate a Hidden Representation Alignment loss to directly align selected teacher–student layers. Experiments show that MTA consistently outperforms state-of-the-art baselines on standard benchmarks, with ablations confirming the contribution of each component.

Yuxing Lu, Xukai Zhao, J. Ben Tamo, Micky C. Nnamdi, Rui Peng, Shuang Zeng, Xingyu Hu, Jinzhuo Wang, May Dongmei Wang

Large Language Models (LLMs) have demonstrated remarkable capabilities on general text; however, their proficiency in specialized scientific domains that require deep, interconnected knowledge remains largely uncharacterized. Metabolomics presents unique challenges with its complex biochemical pathways, heterogeneous identifier systems, and fragmented databases. To systematically evaluate LLM capabilities in this domain, we introduce MetaBench, the first benchmark for metabolomics assessment. Curated from authoritative public resources, MetaBench evaluates five capabilities essential for metabolomics research: knowledge, understanding, grounding, reasoning, and research. Our evaluation of 25 open- and closed-source LLMs reveals distinct performance patterns across metabolomics tasks: while models perform well on text generation tasks, cross-database identifier grounding remains challenging even with retrieval augmentation. Model performance also decreases on long-tail metabolites with sparse annotations. With MetaBench, we provide essential infrastructure for developing and evaluating metabolomics AI systems, enabling systematic progress toward reliable computational tools for metabolomics research.

Parker Seegmiller, Joseph Gatto, Sarah E. Greer, Ganza Belise Isingizwe, Rohan Ray, Timothy E. Burdick, Sarah Masud Preum

Large language models (LLMs) show promise in drafting responses to patient portal messages, yet their integration into clinical workflows raises various concerns, including whether they would actually save clinicians time and effort in their portal workload. We investigate LLM alignment with individual clinicians through a comprehensive evaluation of the patient message response drafting task. We develop a novel taxonomy of thematic elements in clinician responses and propose a novel evaluation framework for assessing clinician editing load of LLM-drafted responses at both content and theme levels. We release an expert-annotated dataset and conduct large-scale evaluations of local and commercial LLMs using various adaptation techniques including thematic prompting, retrieval-augmented generation, supervised fine-tuning, and direct preference optimization. Our results reveal substantial epistemic uncertainty in aligning LLM drafts with clinician responses. While LLMs demonstrate capability in drafting certain thematic elements, they struggle with clinician-aligned generation in other themes, particularly question asking to elicit further information from patients. Theme-driven adaptation strategies yield improvements across most themes. Our findings underscore the necessity of adapting LLMs to individual clinician preferences to enable reliable and responsible use in patient-clinician communication workflows.

Sihong Wu, Owen Jiang, Yilun Zhao, Tiansheng Hu, Yiling Ma, Kaiyan Zhang, Manasi Patwardhan, Arman Cohan

Peer review is a multi-stage process involving reviews, rebuttals, meta-reviews, final decisions, and subsequent manuscript revisions. Recent advances in large language models (LLMs) have motivated methods that assist or automate different stages of this pipeline. In this survey, we synthesize techniques for (i) peer review generation, including fine-tuning strategies, agent-based systems, RL-based methods, and emerging paradigms to enhance generation; (ii) after-review tasks including rebuttals, meta-review and revision aligned to reviews; and (iii) evaluation methods spanning human-centered, reference-based, LLM-based and aspect-oriented. We catalog datasets, compare modeling choices, and discuss limitations, ethical concerns, and future directions. The survey aims to provide practical guidance for building, evaluating, and integrating LLM systems across the full peer review workflow.

Abdellah EL Mekki, Samar M. Magdy, Houdaifa Atou, Ruwa AbuHweidi, Baraah Qawasmeh, Omer Nacar, Thikra Al-hibiri, Razan Saadie, Hamzah A. Alsayadi, Nadia Ghezaiel Hammouda 等

Arabic is a highly diglossic language where most daily communication occurs in regional dialects rather than Modern Standard Arabic (MSA). Despite this, machine translation (MT) systems often generalize poorly to dialectal input, limiting their utility for millions of speakers. We introduce Alexandria, a large-scale, community-driven, human-translated dataset designed to bridge this gap. Alexandria covers 13 Arab countries and 11 high-impact domains, including health, education, and agriculture. Unlike previous resources, Alexandria provides unprecedented granularity by associating contributions with city-of-origin metadata, capturing authentic local varieties beyond coarse regional labels. The dataset consists of parallel English-Dialectal Arabic multi-turn conversational scenarios annotated with speaker-addressee gender configurations, enabling the study of gender-conditioned variation in dialectal use. Comprising 107K total turns, Alexandria serves as both a training resource and as a rigorous benchmark for evaluating MT and Large Language Models (LLMs). Our automatic and human evaluation benchmarks the current capabilities of Arabic-aware LLMs in translating across diverse Arabic dialects and sub-dialects while exposing significant persistent challenges.The Alexandria dataset, the creation prompts, the translation and revision guidelines, and the evaluation code are publicly available in the following repository: https://github.com/UBC-NLP/Alexandria

Zihan Gu, TianYi Zhang, Xinyan Zhang, Zhiyuan Wang, Han Zhang, Yuhao Wei, Jiacheng Lu, Tianyi Ma, Xingsheng Zhang, Hua Zhang 等

Model editing provides a promising mechanism for updating large language models (LLMs) without expensive retraining. Existing approaches, particularly locate-and-edit methods based on least-squares optimization, aim to introduce targeted knowledge changes while preserving pre-trained behavior. In this work, we show that this objective is fundamentally fragile under standard single-edit evaluation protocols. We first develop a unified theoretical framework that characterizes activation-based editing as a constrained intervention on intermediate representations. Within this framework, we demonstrate that least-squares edits cannot, in general, isolate target updates from unrelated activations, giving rise to unavoidable interference that accumulates with successive edits. Crucially, this degradation can remain undetected in single-edit settings when assessed using conventional success and locality metrics. To expose such hidden instabilities, we introduce an uncertainty-based evaluation protocol that combines structured semantic perturbations with uncertainty quantification based on Sampling with Perturbation for UQ. By measuring edit-induced growth in aleatoric and epistemic uncertainty, our method reveals local knowledge conflicts that are invisible to existing benchmarks. Extensive experiments across multiple models, datasets, and editing algorithms show that both least-squares and other parameter-update-based methods consistently increase post-edit uncertainty. Together, our results suggest that current evaluation practices substantially overestimate the reliability of single-edit model editing, and that uncertainty-based diagnostics are necessary for assessing edit stability.

Xueyang Zhou, Weidong Wang, Lin Lu, Jiawen Shi, Guiyao Tie, Xu Yongtian, Lixing Chen, Pan Zhou, Neil Zhenqiang Gong, Lichao Sun

LLM-based agents are rapidly being deployed in real-world applications (e.g., digital assistants and customer service), making safety a critical concern. However, in multi-turn, tool-augmented settings, dynamic user interactions, external tool use, and unintended harmful behaviors make robust safety assurance challenging. To address these challenges, we propose **SafeAgent**, a framework that improves agent safety through fully automated synthetic data generation. SafeAgent introduces (1) an open and extensible threat model OTS that decomposes agent risk into instruction-, context-, and action-induced sources to ground safety analysis and alignment; and (2) an automated pipeline that instantiates OTS to surface scenario-specific failure modes, stress-test agents, and generate self-reflective safe responses—without hazardous real-world data collection. We evaluate SafeAgent on two safety benchmarks and one real-world terminal task. Across four widely used open-source models, SafeAgent improves safety performance by 45% on average and delivers a 28.91% gain on the real-world task, outperforming state-of-the-art closed-source models. These results highlight the practical advancement and scalability of SafeAgent in building safer LLM agents for real-world deployment.

Hongxin Ding, Baixiang Huang, Yue Fang, Weibin Liao, Xinke Jiang, Jinyang Zhang, Yinghao Zhu, Zheng Li, Liantao Ma, Junfeng Zhao 等

Interactive medical questioning is essential in clinical consultations, where physicians must actively gather necessary patient information. Yet existing medical Large Language Models (LLMs) predominantly follow a reactive paradigm, risking diagnostic errors by answering before seeking sufficient details. To bridge this gap, we propose ProMed, a reinforcement learning framework that transitions LLMs toward a proactive paradigm, enabling them to ask clinically valuable questions before decision-making. Central to ProMed is the Shapley Information Gain (SIG) reward, which quantifies a question’s clinical utility as the amount of newly acquired information, while considering its contextual importance via Shapley values. We integrate SIG into a two-stage training pipeline: (1) SIG-Guided Model Initialization uses Monte Carlo Tree Search to construct high-reward interaction trajectories for supervision, and (2) SIG-Augmented Policy Optimization, with a novel SIG-guided Reward Distribution Mechanism that prioritizes informative questions for fine-grained optimization. Experiments on partial-information medical benchmarks show that ProMed significantly outperforms state-of-the-art methods by 6.29% on average and delivers a 54.45% gain over the reactive paradigm, and generalizes robustly to out-of-domain cases. Our codes are available at https://github.com/hxxding/ProMed.