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Yong Sun, Zhengjie Zhang, Junyu Shi, Zhiyuan Zhang, Lijiang Liu, Qiang Nie

Identification of fine-grained embryo developmental stages during In Vitro Fertilization (IVF) is crucial for assessing embryo viability. Although recent deep learning methods have achieved promising accuracy, existing discriminative models fail to utilize the distributional prior of embryonic development to improve accuracy. Moreover, their reliance on single-focal information leads to incomplete embryonic representations, making them susceptible to feature ambiguity under cell occlusions. To address these limitations, we propose EmbryoDiff, a two-stage diffusion-based framework that formulates the task as a conditional sequence denoising process. Specifically, we first train and freeze a frame-level encoder to extract robust multi-focal features. In the second stage, we introduce a Multi-Focal Feature Fusion Strategy that aggregates information across focal planes to construct a 3D-aware morphological representation, effectively alleviating ambiguities arising from cell occlusions. Building on this fused representation, we derive complementary semantic and boundary cues and design a Hybrid Semantic-Boundary Condition Block to inject them into the diffusion-based denoising process, enabling accurate embryonic stage classification. Extensive experiments on two benchmark datasets show that our method achieves state-of-the-art results. Notably, with only a single denoising step, our model obtains the best average test performance, reaching 82.8% and 81.3% accuracy on the two datasets, respectively.

Yifei Sun, Yuzhi He, Junhao Jia, Jinhong Wang, Ruiquan Ge, Changmiao Wang, Hongxia Xu

Microaneurysms (MAs), the earliest pathognomonic signs of Diabetic Retinopathy (DR), present as sub-60 μm lesions in fundus images with highly variable photometric and morphological characteristics, rendering manual screening not only labor-intensive but inherently error-prone. While diffusion-based anomaly detection has emerged as a promising approach for automated MA screening, its clinical application is hindered by three fundamental limitations. First, these models often fall prey to "identity mapping", where they inadvertently replicate the input image. Second, they struggle to distinguish MAs from other anomalies, leading to high false positives. Third, their suboptimal reconstruction of normal features hampers overall performance. To address these challenges, we propose a Wavelet Diffusion Transformer framework for MA Detection (WDT-MD), which features three key innovations: a noise-encoded image conditioning mechanism to avoid "identity mapping" by perturbing image conditions during training; pseudo-normal pattern synthesis via inpainting to introduce pixel-level supervision, enabling discrimination between MAs and other anomalies; and a wavelet diffusion Transformer architecture that combines the global modeling capability of diffusion Transformers with multi-scale wavelet analysis to enhance reconstruction of normal retinal features. Comprehensive experiments on the IDRiD and e-ophtha MA datasets demonstrate that WDT-MD outperforms state-of-the-art methods in both pixel-level and image-level MA detection. This advancement holds significant promise for improving early DR screening.

Yanxiao Sun, Jiafu Wu, Yun Cao, Chengming Xu, Yabiao Wang, Weijian Cao, Donghao Luo, Chengjie Wang, Yanwei Fu

Diffusion-based or flow-based models have achieved significant progress in video synthesis but require multiple iterative sampling steps, which incurs substantial computational overhead. While many distillation methods that are solely based on trajectory-preserving or distribution-matching have been developed to accelerate video generation models, these approaches often suffer from performance breakdown or increased artifacts in few-step settings. To address these limitations, we propose SwiftVideo, a unified and stable distillation framework that combines the advantages of trajectory-preserving and distribution-matching strategies. Our approach introduces continuous-time consistency distillation to ensure precise preservation of ODE trajectories. Subsequently, We propose a dual-perspective alignment encompassing distribution alignment between synthetic and real data along with trajectory alignment across different inference steps. Our method maintains high-quality video generation while substantially reducing the number of inference steps. Quantitative evaluations on the OpenVid-1M benchmark demonstrate that our method significantly outperforms existing approaches in few-step video generation.

Jianchi Sun, Fei Luo, Wenzhuo Fan, Yu Jiang, Chunxia Xiao

Reconstructing fine-grained geometry of clothed human from single-view image is a challenging task, particularly in accurately recovering complex shapes and generating clothes details. To address these limitations, we propose a novel approach named HumanPro, which estimates high-quality human normals via a generative model, and progressively deforms a parametric body into the final clothed human mesh guided by normals. First, we propose a geometry-aware latent diffusion model with a normal enhancer to estimate high-quality human normals from four views. Then, we propose a progressive mesh optimization consisting of shape-aware deformation alignment and global-to-patch detail refinement for human mesh reconstruction. The shape-aware deformation alignment applies image morphing to learn the shape-level gap of normals, addressing large-scale deformation of complex clothes. It can recover the overall silhouette of a clothed human, and serves as an initialization for the global-to-patch detail refinement. Our detail refinement combines global and patch-wise optimization strategies to iteratively produce the clothed human mesh by minimizing the pixel-level difference of normals. This way effectively recovers fine-grained details while avoiding local minima. Extensive experiments demonstrate that HumanPro can deal with various challenging scenarios and outperforms state-of-the-art methods.

Shiyan Su, Ruyi Zha, Danli Shi, Hongdong Li, Xuelian Cheng

Neural representations (NRs), such as neural fields and 3D Gaussians, effectively model volumetric data in computed tomography (CT) but suffer from severe artifacts under sparse-view settings. To address this, we propose DiffNR, a novel framework that enhances NR optimization with diffusion priors. At its core is SliceFixer, a single-step diffusion model designed to correct artifacts in degraded slices. We integrate specialized conditioning layers into the network and develop tailored data curation strategies to support model finetuning. During reconstruction, SliceFixer periodically generates pseudo-reference volumes, providing auxiliary 3D perceptual supervision to fix underconstrained regions. Compared to prior methods that embed CT solvers into time-consuming iterative denoising, our repair-and-augment strategy avoids frequent diffusion model queries, leading to better runtime performance. Extensive experiments show that DiffNR improves PSNR by 3.99 dB on average, generalizes well across domains, and maintains efficient optimization.

Xue Song, Zhongqi Yue, Jiequan Cui, Hanwang Zhang, Jingjing Chen

We tackle the task of customized image editing using a text-conditioned Diffusion Model (DM). The goal is to fuse the subject in a reference image (e.g., sunglasses) with a source one (e.g., a boy), while retaining the fidelity of them both (e.g., the boy wearing the sunglasses). An intuitive approach, called LoRA fusion, first separately trains a DM LoRA for each image to encode its details. Then the two LoRAs are linearly combined by a weight to generate a fused image. Unfortunately, even through careful grid search or learning the weight, this approach still trades off the fidelity of one image against the other. We point out that the evil lies in the overlooked role of diffusion time-step in the generation process, i.e., a smaller time-step controls the generation of a more fine-grained attribute. For example, a large LoRA weight for the source may help preserve its fine-grained details (e.g., face attributes) at a small time-step, but could overpower the reference subject LoRA and lose the fidelity of its overall shape at a larger time-step. To address this deficiency, we propose TimeFusion, which learns a time-step-specific LoRA fusion weight that resolves the trade-off, i.e., generating the source and reference subject in high fidelity given their respective prompt. Then we can customize image editing using this weight and a target prompt.

Xinyang Song, Libin Wang, Weining Wang, Shaozhen Liu, Dandan Zheng, Jingdong Chen, Qi Li, Zhenan Sun

The remarkable success of diffusion models in text-to-image generation has sparked growing interest in expanding their capabilities to a variety of multi-modal tasks, including image understanding, manipulation, and perception. These tasks require advanced semantic comprehension across both visual and textual modalities, especially in scenarios involving complex semantic instructions. However, existing approaches often rely heavily on vision-language models (VLMs) or modular designs for semantic guidance, leading to fragmented architectures and computational inefficiency. To address these challenges, we propose UniAlignment, a unified multimodal generation framework within a single diffusion transformer. UniAlignment introduces a dual-stream diffusion training strategy that incorporates both intrinsic-modal semantic alignment and cross-modal semantic alignment, thereby enhancing the model's cross-modal consistency and instruction-following robustness. Additionally, we present SemGen-Bench, a new benchmark specifically designed to evaluate multimodal semantic consistency under complex textual instructions. Extensive experiments across multiple tasks and benchmarks demonstrate that UniAlignment outperforms existing baselines, underscoring the significant potential of diffusion models in unified multimodal generation.

Wensong Song, Hong Jiang, Zongxin Yang, Zheqiao Cheng, Ruijie Quan, Yi Yang

This work presents Insert Anything, a unified framework for reference-based image insertion that seamlessly integrates objects from reference images into target scenes under flexible, user-specified control guidance. Instead of training separate models for individual tasks, our approach is trained once on our new AnyInsertion dataset, the first open-source large-scale dataset specifically designed for reference image–based image editing, comprising 136K prompt-image pairs covering diverse tasks such as person, object, and garment insertion--and effortlessly generalizes to a wide range of insertion scenarios. Such a challenging setting requires capturing both identity features and fine-grained details, while allowing versatile local adaptations in style, color, and texture. To this end, we propose to leverage the multimodal attention of the Diffusion Transformer (DiT) to support both mask- and text-guided editing. Furthermore, we introduce an in-context editing mechanism that treats the reference image as contextual information, employing two prompting strategies to harmonize the inserted elements with the target scene while faithfully preserving their distinctive features. Extensive experiments on AnyInsertion, DreamBooth, and VTON-HD benchmarks demonstrate that our method consistently outperforms existing alternatives, underscoring its great potential in real-world applications such as creative content generation, virtual try-on, and scene composition.

Vera Soboleva, Aibek Alanov, Andrey Kuznetsov, Konstantin Sobolev

While diffusion model fine-tuning offers a powerful approach for customizing pre-trained models to generate specific objects, it frequently suffers from overfitting when training samples are limited, compromising both generalization capability and output diversity. This paper tackles the challenging yet most impactful task of adapting a diffusion model using just a single concept image, as single-image customization holds the greatest practical potential. We introduce T-LoRA, a Timestep-Dependent Low-Rank Adaptation framework specifically designed for diffusion model personalization. In our work we show that higher diffusion timesteps are more prone to overfitting than lower ones, necessitating a timestep-sensitive fine-tuning strategy. T-LoRA incorporates two key innovations: (1) a dynamic fine-tuning strategy that adjusts rank-constrained updates based on diffusion timesteps, and (2) a weight parametrization technique that ensures independence between adapter components through orthogonal initialization. Extensive experiments show that T-LoRA and its individual components outperform standard LoRA and other diffusion model personalization techniques. They achieve a superior balance between concept fidelity and text alignment, highlighting the potential of T-LoRA in data-limited and resource-constrained scenarios.

Xincheng Shuai, Zhenyuan Qin, Henghui Ding, Dacheng Tao

Recent advances in text-to-image (T2I) diffusion models have significantly improved semantic image editing, yet most methods fall short in performing 3D-aware object manipulation. In this work, we present FFSE, a 3D-aware autoregressive framework designed to enable intuitive, physically-consistent object editing directly on real-world images. Unlike previous approaches that either operate in image space or require slow and error-prone 3D reconstruction, FFSE models editing as a sequence of learned 3D transformations, allowing users to perform arbitrary manipulations, such as translation, scaling, and rotation, while preserving realistic background effects (e.g., shadows, reflections) and maintaining global scene consistency across multiple editing rounds. To support learning of multi-round 3D-aware object manipulation, we introduce 3DObjectEditor, a hybrid dataset constructed from simulated editing sequences across diverse objects and scenes, enabling effective training under multi-round and dynamic conditions. Extensive experiments show that the proposed FFSE significantly outperforms existing methods in both single-round and multi-round 3D-aware editing scenarios.

Chunlei Shi, Han Xu, Yinghao Li, Yi-Lin Wei, Yongchao Feng, Yecheng Zhang, Dan Niu

Satellite-based radar retrieval methods are widely employed to fill coverage gaps in ground-based radar systems, especially in remote areas affected by terrain blockage and limited detection range. Existing methods predominantly rely on overly simplistic spatial-domain architectures constructed from a single data source, limiting their ability to accurately capture complex precipitation patterns and sharply defined meteorological boundaries. To address these limitations, we propose WaveC2R, a novel wavelet-driven coarse-to-refined framework for radar retrieval. WaveC2R integrates complementary multi-source data and leverages frequency-domain decomposition to separately model low-frequency components for capturing precipitation patterns and high-frequency components for delineating sharply defined meteorological boundaries. Specifically, WaveC2R consists of two stages (i) Intensity-Boundary Decoupled Learning, which leverages wavelet decomposition and frequency-specific loss functions to separately optimize low-frequency intensity and high-frequency boundaries; and (ii) Detail-Enhanced Diffusion Refinement, which employs frequency-aware conditional priors and multi-source data to progressively enhance fine-scale precipitation structures while preserving coarse-scale meteorological consistency. Experimental results on the publicly available SEVIR dataset demonstrate that WaveC2R achieves state-of-the-art performance in satellite-based radar retrieval, particularly excelling at preserving high-intensity precipitation features and sharply defined meteorological boundaries.

Chuancheng Shi, Shiming Guo, Ke Shui, Yixiang Chen, Fei Shen

Diffusion-based generative models have demonstrated remarkable capabilities in image synthesis, yet realistic hand generation remains a persistent challenge due to complex articulations, self-occlusion, and the lack of explicit structural guidance. To address these issues, we present SGMHand, a novel structure-guided hand inpainting framework that explicitly injects topological priors to enhance structural fidelity and spatial precision. Specifically, we present a structure-guided modulation (SGM) module that synergistically combines structure spatial attention with global feature calibration, enabling fine-grained geometric control over the generative process. Then, we devise a keypoint-aware (KA) loss that enforces topological coherence by aligning attention activations with structures, thereby bridging the gap between high-level semantics and low-level geometry. By jointly optimizing over structural constraints in both representation and learning objectives, SGMHand achieves semantically consistent and geometrically plausible hand synthesis, even under severe occlusion. Extensive experiments demonstrate the effectiveness and strong generalization ability of SGMHand across various foundation models, significantly enhancing the quality and realism of human image synthesis in diverse scenarios.

Kaixin Shen, Ruijie Quan, Jiaxu Miao, Jun Xiao

The rapid advancement of diffusion-based image editing has enabled highly controllable visual content generation but has also raised serious concerns about the misuse of generative models for producing Not-Safe-for-Work (NSFW) content. Existing protection strategies inject adversarial perturbations to disrupt editing. However, these methods are untargeted, often degrading benign edits while failing to eliminate harmful outputs. In this work, we propose TarPro, a targeted protection framework that blocks malicious edits while preserving benign editing functionality. TarPro introduces Dual-Intent Optimization (DIO), a semantic alignment objective that suppresses malicious prompt effects while retaining desirable, benign edits, by leveraging prompt compositionality rather than requiring manually annotated preferences. To ensure robustness and generalization, we replace pixel-level optimization with a generator-based perturbation learning strategy that learns to produce structured, imperceptible perturbations in parameter space. Experiments on multiple diffusion backbones show that TarPro significantly blocks NSFW content while maintaining high-quality benign edits, outperforming strong baselines through both qualitative and quantitative evaluations.

Yihua Shao, Deyang Lin, Minxi Yan, Siyu Chen, Fanhu Zeng, Minwen Liao, Ao Ma, Ziyang Yan, Haozhe Wang, Yan Wang 等

Diffusion models have been widely adopted in image and video generation. However, their complex network architecture leads to high inference overhead for its generation process. Existing diffusion quantization methods primarily focus on the quantization of the model structure while ignoring the impact of time-steps variation during sampling. At the same time, most current approaches fail to account for significant activations that cannot be eliminated, resulting in substantial performance degradation after quantization. To address these issues, we propose Time-Rotation Diffusion Quantization (TR-DQ), a novel quantization method incorporating time-step and rotation-based optimization. TR-DQ first divides the sampling process based on time-steps and applies a rotation matrix to smooth activations and weights dynamically. For different time-steps, a dedicated hyperparameter is introduced for adaptive timing modeling, which enables dynamic quantization across different time steps. Additionally, we also explore the compression potential of Classifier-Free Guidance (CFG-wise) to establish a foundation for subsequent work. TR-DQ achieves state-of-the-art (SOTA) performance on image generation and video generation tasks and a 1.38-1.89× speedup and 1.97-2.58× memory reduction in inference compared to existing quantization methods.

Sheng Shang, Chenglong Zhao, Ruixin Zhang, Jianlong Jin, Jingyun Zhang, Jun Wang, Yang Zhao, Shouhong Ding, Wei Jia

Palm vein recognition has emerged as a promising biometric technology, yet its development remains constrained by the scarcity of large-scale publicly available datasets. Several methods of palm vein image generation have been proposed to address this issue. These methods usually focus on the anatomical realism of palm vein patterns, but overlook the biophysical correlation between identities and vein patterns, particularly in simulating identity-specific vein contrast. To tackle this limitation, we propose a novel biophysics-driven synthesis method. Our method constructs a 3D palm vascular tree via established modeling method. Then, a projection model is proposed to map the 3D tree into 2D space to derive palm vein patterns. The projection model is based on skin spectral absorption and simulates the natural attenuation of light passing through the skin using a layer integration method. For different identities, we sample different skin parameters, resulting in varying degrees of attenuation. This method effectively simulates the variation in vein contrast across different identities. Furthermore, we introduce a conditional diffusion model that uses the projected patterns as identity conditions to generate palm vein images. To the best of our knowledge, this is the first palm vein generation method based on the diffusion model. Experimental results demonstrate that our method not only outperforms existing methods, but also enables a recognition model trained on our synthetic data to achieve superior performance compared to a model trained on real-world data at a scale of 2,000 IDs under an open-set protocol with a TAR@FAR=1:1 of 1e-4.

Alec Sargood, Lemuel Puglisi, James H Cole, Neil P. Oxtoby, Daniele Ravì, Daniel C. Alexander

Synthesizing amyloid PET scans from the more widely available and accessible structural MRI modality offers a promising, cost-effective approach for large-scale Alzheimer's Disease (AD) screening. This is motivated by evidence that, while MRI does not directly detect amyloid pathology, it may nonetheless encode information correlated with amyloid deposition that can be uncovered through advanced modeling. However, the high dimensionality and structural complexity of 3D neuroimaging data pose significant challenges for existing MRI-to-PET translation methods. Modeling the cross-modality relationship in a lower-dimensional latent space can simplify the learning task and enable more effective translation. As such, we present CoCoLIT (ControlNet-Conditioned Latent Image Translation), a diffusion-based latent generative framework that incorporates three main innovations: (1) a novel Weighted Image Space Loss (WISL) that improves latent representation learning and synthesis quality; (2) a theoretical and empirical analysis of Latent Average Stabilization (LAS), an existing technique used in similar generative models to enhance inference consistency; and (3) the introduction of ControlNet-based conditioning for MRI-to-PET translation. We evaluate CoCoLIT's performance on publicly available datasets and find that our model significantly outperforms state-of-the-art methods on both image-based and amyloid-related metrics. Notably, in amyloid-positivity classification, CoCoLIT outperforms the second-best method with improvements of +10.5% on the internal dataset and +23.7% on the external dataset.

Yansong Qu, Shaohui Dai, Xinyang Li, Yuze Wang, You Shen, Shengchuan Zhang, Liujuan Cao

Reconstructing 3D objects from a single image is a long-standing challenge, particularly under real-world occlusions. While recent diffusion-based view synthesis models can generate consistent novel views from a single RGB image, they generally assume fully visible inputs and struggle when parts of the object are occluded, leading to inconsistent views and degraded 3D reconstruction quality. To address this limitation, we propose DeOcc-1-to-3, an end-to-end framework for occlusion-aware multi-view generation. Our method directly synthesizes six structurally consistent novel views from a single partially occluded image, enabling downstream 3D reconstruction without requiring prior inpainting or manual annotations. We design a self-supervised training pipeline that leverages occluded–unoccluded image pairs and pseudo-ground-truth views to guide structure-aware completion and view consistency. Without modifying the original architecture, we fully fine-tune the diffusion model to jointly learn completion and multi-view generation. Additionally, we introduce the first benchmark for occlusion-aware reconstruction, covering diverse occlusion levels, object categories, and mask patterns, providing a standardized evaluation protocol.

Wentao Qu, Guofeng Mei, Jing Wang, Yujiao Wu, Xiaoshui Huang, Liang Xiao

Denoising Diffusion Probabilistic Models (DDPMs) have shown success in robust 3D object detection tasks. Existing methods often rely on the score matching from 3D boxes or pre-trained diffusion priors. However, they typically require multi-step iterations in inference, which limits efficiency. To address this, we propose a Robust single-stage fully Sparse 3D object Detection Network with a Detachable Latent Framework (DLF) of DDPMs, named RSDNet. Specifically, RSDNet learns the denoising process in latent feature spaces through lightweight denoising networks like multi-level denoising autoencoders (DAEs). This enables RSDNet to effectively understand scene distributions under multi-level perturbations, achieving robust and reliable detection. Meanwhile, we reformulate the noising and denoising mechanisms of DDPMs, enabling DLF to construct multi-type and multi-level noise samples and targets, enhancing RSDNet robustness to multiple perturbations. Furthermore, a semantic-geometric conditional guidance is introduced to perceive the object boundaries and shapes, alleviating the center feature missing problem in sparse representations, enabling RSDNet to perform in a fully sparse detection pipeline. Moreover, the detachable denoising network design of DLF enables RSDNet to perform single-step detection in inference, further enhancing detection efficiency. Extensive experiments on public benchmarks show that RSDNet can outperform existing methods, achieving state-of-the-art detection.

Yuhang Qian, Haiyan Chen, Wentong Li, Ningzhong Liu, Jie Qin

Camouflage Images Generation (CIG) is an emerging research area that focuses on synthesizing images in which objects are harmoniously blended and exhibit high visual consistency with their surroundings. Existing methods perform CIG by either fusing objects into specific backgrounds or outpainting the surroundings via foreground object-guided diffusion. However, they often fail to obtain natural results because they overlook the logical relationship between camouflaged objects and background environments. To address this issue, we propose CT-CIG, a Controllable Text-guided Camouflage Images Generation method that produces realistic and logically plausible camouflage images. Leveraging Large Visual Language Models (VLM), we design a Camouflage-Revealing Dialogue Mechanism (CRDM) to annotate existing camouflage datasets with high-quality text prompts. Subsequently, the constructed image-prompt pairs are utilized to finetune Stable Diffusion, incorporating a lightweight controller to guide the location and shape of camouflaged objects for enhanced camouflage scene fitness. Moreover, we design a Frequency Interaction Refinement Module (FIRM) to capture high-frequency texture features, facilitating the learning of complex camouflage patterns. Extensive experiments, including CLIPScore evaluation and camouflage effectiveness assessment, demonstrate the semantic alignment of our generated text prompts and CT-CIG's ability to produce photorealistic camouflage images.

Chenghao Qian, Wenjing Li, Yuhu Guo, Gustav Markkula

In this work, we present WeatherEdit, a novel weather editing pipeline for generating realistic weather effects with controllable types and severity in 3D scenes. Our approach is structured into two key components: weather background editing and weather particle construction. For weather background editing, we introduce an all-in-one adapter that integrates multiple weather styles into a single diffusion model, enabling the generation of diverse weather effects in 2D image backgrounds. During inference, we design a Temporal-View (TV-) attention mechanism that follows a specific order to aggregate temporal and spatial information, ensuring consistent editing across multi-frame and multi-view images. To construct the weather particles, we first reconstruct a 3D scene using the edited images and then introduce a 4D Gaussian field to generate snowflakes, raindrops and fog in the scene. The attributes and dynamics of these particles are controlled through attribute modelling and dynamic simulation, ensuring realistic weather representation and flexible severity adjustments. Finally, we integrate the 4D Gaussian field with the 3D scene to render consistent and highly realistic weather effects. Experiments on multiple driving datasets demonstrate that WeatherEdit can generate diverse weather effects with controllable condition severity, highlighting its potential for autonomous driving simulation in adverse weather.