Understanding the structural dynamics of biomolecules is crucial for uncovering biological functions. As molecular dynamics (MD) simulation data becomes more available, deep generative models have been developed to synthesize realistic MD trajectories. However, existing methods produce fixed-length trajectories by jointly denoising high-dimensional spatiotemporal representations, which conflicts with MD’s frame-by-frame integration process and fails to capture time-dependent conformational diversity. Inspired by MD's sequential nature, we introduce a new probabilistic autoregressive (ProAR) framework for trajectory generation. ProAR uses a dual-network system that models each frame as a multivariate Gaussian distribution and employs an anti-drifting sampling strategy to reduce cumulative errors. This approach captures conformational uncertainty and time-coupled structural changes while allowing flexible generation of trajectories of arbitrary length. Experiments on ATLAS, a large-scale protein MD dataset, demonstrate that for long trajectory generation, our model achieves a 7.5% reduction in reconstruction RMSE and an average 25.8% improvement in conformation change accuracy compared to previous state-of-the-art methods. For conformation sampling task, it performs comparably to specialized time-independent models, providing a flexible and dependable alternative to standard MD simulations.
论文检索
输入标题、作者或关键词,从 8,216 篇学术成果中精准定位
Toward Multimodal Fake News Detection by Multi-perspective Rationale Generation and Verification
PDF ↗The rapid proliferation of social media platforms has led to a surge in multimodal fake news, where deceptive content often combines text and images to mislead audiences. Traditional unimodal detection methods struggle to address the complexity of such content, necessitating holistic multimodal approaches. While the latest advancements in Multimodal Large Language Models (MLLMs) offer new opportunities for enhancing detection performance by analyzing multi-dimensional features, including source credibility, cross-modal contradictions, emotional bias, and manipulative writing patterns, these methods suffer from a key flaw: a susceptibility to hallucinations or erroneous reasoning, which can lead to flawed conclusions and ultimately biased detection results. We propose the Multimodal Fake News Detection via Multi-perspective Rationale Generation and Verification (MMRGV) model to mitigate this challenge. Our method employs a cross-verification mechanism to screen and reconcile contradictions among different rationales, thereby preserving the LLM's analytical advantages while mitigating the impact of erroneous reasoning or hallucinations on the final detection. Subsequently, these optimized rationales are fused via an adaptive weighting strategy to output a robust final prediction. Extensive experiments on three benchmark datasets (Twitter, Weibo, and GossipCop) demonstrate the superiority of our method, achieving state-of-the-art accuracy of 0.9972, 0.9663, and 0.8772, respectively, and significantly outperforming existing baselines. These results validate the effectiveness of multi-perspective rationale generation and cross-verification in enhancing multimodal fake news detection, offering a resilient solution to combat misinformation in the era of generative AI.
SAME: Sparse and Anchored Model Editing for Heterogeneous Incremental Learning under Limited Data
PDF ↗Existing Incremental Learning (IL) methods are primarily evaluated under either a single-domain class-incremental setting, or a multi-domain task-incremental setting with known task identifiers. However, these assumptions often fail to hold in real-world applications. To bridge this gap, we introduce Heterogeneous Incremental Learning (HIL), a new setting for evaluating IL methods under realistic and challenging conditions, where task boundaries are ambiguous or unknown, class distributions shift dynamically across environments, and training data is limited. Model editing is inherently well-suited for this challenging HIL, as it allows for the efficient integration of new knowledge while preserving model capabilities. Thus, we propose a novel Sparse and Anchored Model Editing (SAME) for addressing HIL. Specifically, SAME sparsely and selectively updates task-relevant model parameters to extract compact, task-specific key-value knowledge pairs from limited data. Using these task knowledge pairs, the model performs knowledge injection for new tasks under double-anchor constraints. The knowledge anchor aligns the updated and original model features, while the parameter anchor constrains parameter magnitudes, ensuring stable and consistent knowledge injection. Our method can efficiently solve HIL using only a few labeled examples, without introducing additional model parameters. Extensive experiments on 11 diverse visual-language datasets across 22 sequential tasks show that our method outperforms existing continual learning approaches by 6.8% in average accuracy, while retaining 95.8% of the oracle model performance, demonstrating strong stability and cross-domain generalization.
The Power of Decaying Steps: Enhancing Attack Stability and Transferability for Sign-based Optimizers
PDF ↗Crafting adversarial examples can be formulated as an optimization problem. While sign-based optimizers such as I-FGSM and MI-FGSM have become the de facto standard for the induced optimization problems, there still exist several unsolved problems in theoretical grounding and practical reliability especially in non-convergence and instability, which inevitably influences their transferability. Contrary to the expectation, we observe that the attack success rate may degrade sharply when more number of iterations are conducted. In this paper, we address these issues from an optimization perspective. By reformulating the sign-based optimizer as a specific coordinate-wise gradient descent, we argue that one cause for non-convergence and instability is their non-decaying step-size scheduling. Based upon this viewpoint, we propose a series of new attack algorithms that enforce Monotonically Decreasing Coordinate-wise Step-sizes (MDCS) within sign-based optimizers. Typically, we further provide theoretical guarantees proving that MDCS-MI attains an optimal convergence rate of O(1/\sqrt T ), where T is the number of iterations. Extensive experiments on image classification and cross-modal retrieval tasks demonstrate that our approach not only significantly improves transferability but also enhances attack stability compared to state-of-the-art sign-based methods.
Vision-Language Attribute Disentanglement and Reinforcement for Lifelong Person Re-Identification
PDF ↗Lifelong person re-identification (LReID) aims to learn from varying domains to obtain a unified person retrieval model. Existing LReID approaches typically focus on learning from scratch or a visual classification-pretrained model, while the Vision-Language Model (VLM) has shown generalizable knowledge in a variety of tasks. Although existing methods can be directly adapted to the VLM, since they only consider global-aware learning, the fine-grained attribute knowledge is underleveraged, leading to limited acquisition and anti-forgetting capacity. To address this problem, we introduce a novel VLM-driven LReID approach named Vision-Language Attribute Disentanglement and Reinforcement (VLADR). Our key idea is to explicitly model the universally shared human attributes to improve inter-domain knowledge transfer, thereby effectively utilizing historical knowledge to reinforce new knowledge learning and alleviate forgetting. Specifically, VLADR includes a Multi-grain Text Attribute Disentanglement mechanism that mines the global and diverse local text attributes of an image. Then, an Inter-domain Cross-modal Attribute Reinforcement scheme is developed, which introduces cross-modal attribute alignment to guide visual attribute extraction and adopts inter-domain attribute alignment to achieve fine-grained knowledge transfer. Experimental results demonstrate that our VLADR outperforms the state-of-the-art methods by 1.9%-2.2% and 2.1%-2.5% on anti-forgetting and generalization capacity. Our source code is available at https://github.com/zhoujiahuan1991/CVPR2026-VLADR
Exemplar-Free Class Incremental Learning (EFCIL) aims to enable models to learn new classes sequentially without retaining samples from previous tasks. While recent approaches leverage pre-trained models with parameter-efficient tuning to mitigate forgetting, they often overlook a crucial cause of forgetting: the collapse of the class-discriminative structure. This structure comprises two interdependent components: intra-class structure, which characterizes the shape of individual classes, and inter-class structure, which characterizes the global geometric relationships among class prototypes. We reveal that catastrophic forgetting stems from the simultaneous deterioration of both intra-class and inter-class structures. To address this, we propose a unified framework that preserves the class-discriminative structure. It preserves the intra-class structure by reshaping class means and covariances to preserve each class's shape during migration, and maintains inter-class structure by stabilizing angular relationships between samples and old prototypes. Extensive experiments demonstrate that our framework outperforms existing leading methods on multiple EFCIL benchmarks, validating that preserving the class-discriminative structure is crucial for mitigating catastrophic forgetting.
Motion blur is a common degradation in dynamic imaging. Recent studies have moved beyond restoring a single sharp image from a blurred input and instead target blur decomposition: recovering a temporally continuous sharp video sequence from one motion-blurred image. Event cameras, with their microsecond temporal resolution, can effectively alleviate motion ambiguity. However, existing event-based methods often fail to explicitly model time-aligned event-image features. How to accurately exploit event data to reconstruct frames at different time instants remains largely underexplored. In this paper, we propose TSANet, an event-based blur-to-video decomposition method that time-specializes both event features and image features for alignment. Specifically, we introduce a Relative Time-Encoded Attention module that steers event features toward motion information relevant to a given target time, and a Timesurface Dynamic Warping module that warps image features into the spatial configuration corresponding to that time. With time-specialized motion and image features explicitly aligned at arbitrary query times, our framework can decompose a single blurred image into a high-frame-rate sharp video sequence. In addition, we collect a new dataset containing real events and high-quality color videos, and synthesize blurred inputs by averaging sharp frames to evaluate our method. Experiments on multiple datasets with both synthetic and real events demonstrate that our approach consistently outperforms previous state-of-the-art methods on the blur decomposition task.
Digital hematopathology requires cell-level analysis across diverse disease categories, including malignant disorders (e.g., leukemia), infectious conditions (e.g., malaria), and non-malignant red blood cell disorders (e.g., sickle cell disease). Whether single-task, vision-language, WSI- optimized, or single-cell hematology models, these approaches share a key limitation: they cannot provide unified, multi-task, multi-modal reasoning across the complexities of digital hematopathology. To overcome these limitations, we propose Uni-Hema, a multi-task, unified model for digital hematopathology integrating detection, classification, segmentation, morphology prediction, and reasoning across multiple diseases. Uni-Hema leverages 46 publicly available datasets, encompassing over 700K images and 21K question-answer pairs, and is built upon Hema-Former, a multimodal module that bridges visual and linguistic representations at the hierarchy level for the different tasks (detection, classification, segmentation, morphology, mask language modeling, and visual question answering) at different granularities. Extensive experiments demonstrate that Uni-Hema achieves comparable or superior performance compared to training on a single task and single-dataset models, across diverse hematological tasks, while providing interpretable, morphologically relevant insights at the single-cell level. Our framework establishes a new standard for multi-task and multi-modal digital hematopathology. The code is available at https://github.com/intelligentMachines-ITU/Uni-Hema
Training-free open-vocabulary semantic segmentation (OVSS) promises rapid adaptation to new label sets without retraining. Yet, many methods rely on heavy post-processing or handle text and vision in isolation, leaving cross-modal geometry underutilized. Others introduce auxiliary vision backbones or multi-model pipelines, which increase complexity and latency while compromising design simplicity.We present PEARL, \underline P rocrust\underline e s \underline a lignment with text-awa\underline r e \underline L aplacian propagation, a compact two-step inference that follows an align-then-propagate principle. The Procrustes alignment step performs an orthogonal projection inside the last self-attention block, rotating keys toward the query subspace via a stable polar iteration. The text-aware Laplacian propagation then refines per-pixel logits on a small grid through a confidence-weighted, text-guided graph solve: text provides both a data-trust signal and neighbor gating, while image gradients preserve boundaries. In this work, our method is fully training-free, plug-and-play, and uses only fixed constants, adding minimal latency with a small per-head projection and a few conjugate-gradient steps. Our approach, PEARL, sets a new state-of-the-art in training-free OVSS without extra data or auxiliary backbones across standard benchmarks, achieving superior performance under both with-background and without-background protocols.
Change detection (CD) is a fundamental task for monitoring and analysing land cover dynamics. While recent high performance models and high quality datasets have significantly advanced the field, a critical limitation persists. Current models typically acquire limited knowledge from single-type annotated data and cannot concurrently leverage diverse binary change detection (BCD) and semantic change detection (SCD) datasets. This constraint leads to poor generalisation and limited versatility. The recent advancements in Multimodal Large Language Models (MLLMs) introduce new possibilities for a unified CD framework. We leverage the language priors and unification capabilities of MLLMs to develop UniChange, the first MLLM-based unified change detection model. UniChange integrates generative language abilities with specialised CD functionalities. We introduce three special tokens: [T1], [T2], and [CHANGE], utilising their embeddings as the key to query variations. This approach successfully accommodates both BCD and SCD tasks. Furthermore, UniChange utilises text prompts to guide the identification of change categories, eliminating the reliance on predefined classification heads. This design allows UniChange to effectively acquire knowledge from multi-source datasets, even when their class definitions conflict. Experiments on four public benchmarks (WHU-CD, S2Looking, LEVIR-CD+, and SECOND) demonstrate SOTA performance, achieving IoU scores of 90.41, 53.04, 78.87, and 57.62, respectively, surpassing all previous methods. The code is available at https://github.com/NKU-HLT/UniChange.
Recent advancements in multimodal large language models (MLLMs) and video agent systems have significantly improved general video understanding. However, when applied to scientific video understanding and educating--a domain that demands external professional knowledge integration and rigorous step-wise reasoning--existing approaches often struggle. To bridge this gap, we propose SciEducator, an iterative self-evolving multi-agent system for scientific video comprehension and education. Rooted in the classical Deming Cycle from management science, our design reformulates its Plan-Do-Study-Act philosophy into a self-evolving reasoning and feedback mechanism, which facilitates the interpretation of intricate scientific activities in videos. Moreover, SciEducator can produce multimodal educational content tailored to specific scientific processes, including textual instructions, visual guides, audio narrations, and interactive references. To support evaluation, we construct SciVBench, a benchmark consisting of 500 expert-verified and literature-grounded science QA pairs across five categories, covering physical, chemical, and everyday phenomena. Extensive experiments demonstrate that SciEducator substantially outperforms leading closed-source MLLMs (e.g., Gemini, GPT-4o) and state-of-the-art video agents on the benchmark, establishing a new paradigm for the community.
Precise and controllable image editing remains a significant challenge. Current methods often rely on text prompts, but achieving accurate spatial localization solely through descriptions is inherently difficult. Mask-based approaches, though offering better control, typically require overly precise user annotations, thus increasing user burden and leading to unnatural results. To bridge this gap, we introduce the **I**nteractive **I**nstruction-based **I**mage **E**diting (I^3E) task, which generates high-quality edits from a more intuitive combination: concise text instructions and imprecise spatial guidance. To address the critical lack of suitable data, we propose an efficient pipeline to generate Inter-Edit, a new million-scale training dataset that simulates realistic user masks---not strictly segment-aligned. We also present a comprehensive benchmark, featuring a meticulously human-annotated test set that captures diverse, localization-dependent editing scenarios and realistic user interaction patterns. To evaluate this task, we introduce a new suite of position-aware metrics that strongly correlate with human perceptual judgments. Finally, we develop three baseline models trained on Inter-Edit. Extensive experiments demonstrate that our methods significantly enhance I_3E performance, achieving substantial improvements in localization and edit quality, and outperforming existing state-of-the-art models. The Inter-Edit dataset and all related code are publicly available at https://github.com/Delong-liu-bupt/Inter-Edit.
3D Gaussian splatting (3DGS) has demonstrated impressive performance in synthesizing high-fidelity novel views. Nonetheless, its effectiveness critically depends on the quality of the initialized point cloud. Specifically, achieving uniform and complete point coverage over the underlying scene structure requires overlapping observation frustums, an assumption that is often violated in unbounded, dynamic urban environments. Training Gaussian models with partially initialized point clouds often leads to distortions and artifacts, as camera rays may fail to intersect valid surfaces, resulting in incorrect gradient propagation to Gaussian primitives associated with occluded or invisible geometry. Additionally, existing densification strategies simply clone and split Gaussian primitives from existing ones, incapable of reconstructing geometry from missing structures. To address these limitations, we propose VAD-GS, a 3DGS framework tailored for geometry recovery in challenging urban scenes. Our method identifies unreliable geometry structures via voxel-based visibility reasoning, selects informative supporting views through diversity-aware view selection, and recovers missing structures via multi-view stereo reconstruction. This design enables the generation of new Gaussian primitives guided by reliable geometric priors, even in regions lacking initial points. Extensive experiments on the Waymo and nuScenes datasets demonstrate that VAD-GS outperforms state-of-the-art 3DGS approaches and significantly improves the quality of reconstructed geometry for both static and dynamic objects.Source code will be released upon publication.
Conditional image generation methods are increasingly used in human-centric applications, yet existing human amodal completion (HAC) models offer users limited control over the completed content. Given an occluded person image, they hallucinate invisible regions while preserving visible ones, but cannot reliably incorporate user-specified constraints such as a desired pose or spatial extent. As a result, users often resort to repeatedly sampling the model to obtain a satisfactory output. Pose-guided person image synthesis (PGPIS) methods allow explicit pose conditioning, but frequently fail to preserve the instance-specific visible appearance and tend to be biased toward the training distribution, even when built on strong diffusion model priors. To address these limitations, we introduce promptable human amodal completion (PHAC), a new task that completes occluded human images while satisfying both visible appearance constraints and multiple user prompts. Users provide simple point-based prompts, such as additional joints for the target pose or bounding boxes for desired regions; these prompts are encoded using ControlNet modules specialized for each prompt type. These modules inject the prompt signals into a pre-trained diffusion model, and we fine-tune only the cross-attention blocks to obtain strong prompt alignment without degrading the underlying generative prior. To further preserve visible content, we propose an inpainting-based refinement module that starts from a slightly noised coarse completion, faithfully preserves the visible regions, and ensures seamless blending at occlusion boundaries. Extensive experiments on standard HAC and PGPIS benchmarks show that our approach produces more physically plausible, higher-quality completions with significantly improved prompt alignment compared to existing amodal completion and pose-guided synthesis methods.
3D Referring Expression Segmentation (3D-RES) aims to segment objects in point clouds according to language descriptions. Unlike common practices in 2D that utilize learnable query embeddings, recent 3D-RES methods typically generate queries directly from 3D points. However, this direct coupling of queries to raw point clouds introduces new challenges: an impractically large number of queries derived from massive point cloud data and a reliance on non-deterministic sampling algorithms. In this paper, we propose a Semantic-based Adaptive Query Network (SAQN), which introduces a novel query strategy for 3D-RES. Instead of generating queries from points, SAQN employs a learnable query vector for each semantic class. This approach drastically reduces the number of queries while maintaining the advantage of avoiding Hungarian matching through implicit class alignment. Additionally, to address potential cross-object ambiguity within semantic classes, we introduce supplementary queries that are adaptively fused with each class query to disambiguate and enrich representations. Comprehensive experiments show that SAQN achieves state-of-the-art performance while reducing the number of queries.
Adversarial patches have emerged as a popular privacy-preserving approach for resisting AI-driven surveillance systems. However, their conspicuous appearance makes them difficult to deploy in real-world scenarios. In this paper, we propose a thermally activated adversarial wearable designed to ensure adaptability and effectiveness in complex real-world environments. The system integrates thermochromic dyes with flexible heating units to induce visually dynamic adversarial patterns on clothing surfaces. In its default state, the clothing appears as an ordinary black T-shirt. Upon heating via an embedded thermal unit, hidden adversarial patterns on the fabric are activated, allowing the wearer to effectively evade detection across both visible and infrared modalities. Physical experiments demonstrate that the adversarial wearable achieves rapid texture activation within 50 seconds and maintains an adversarial success rate above 80% across diverse real-world surveillance environments. This work demonstrates a new pathway toward physically grounded, user-controllable anti-AI systems, highlighting the growing importance of proactive adversarial techniques for privacy protection in the age of ubiquitous AI surveillance.
Vision-based robotic policies often struggle with even minor viewpoint changes, underscoring the need for view-invariant visual representations. This challenge becomes more pronounced in real-world settings, where viewpoint variability is unavoidable and can significantly disrupt policy performance. Existing methods typically learn invariance from multi-view observations at the scene level, but such approaches rely on visual appearance and fail to incorporate the physical dynamics essential for robust generalization. We propose View-Invariant Latent Action (VILA), which models a latent action capturing transition patterns across trajectories to learn view-invariant representations grounded in physical dynamics. VILA aligns these latent actions across viewpoints using an action-guided objective based on ground-truth action sequences. Experiments in both simulation and the real world show that VILA-based policies generalize effectively to unseen viewpoints and transfer well to new tasks, establishing VILA as a strong pretraining framework that improves resilience to viewpoint shifts and downstream learning performance.
Learning to See through Illumination Extremes with Event Streaming in Multimodal Large Language Models
PDF ↗Multimodal Large Language Models (MLLMs) perform strong vision-language reasoning under standard conditions but fail in extreme illumination, where RGB inputs lose irrevocable structure and semantics. We propose Event-MLLM, an event-enhanced model that performs all-light visual reasoning by dynamically fusing event streams with RGB frames. Two key components drive our approach: an Illumination Indicator -- a learnable signal derived from a DINOv2 branch that represents exposure degradation and adaptively modulates event-RGB fusion -- and an Illumination Correction Loss that aligns fused features with non-degraded (normal-light) semantics in the latent space, compensating for information lost in extreme lighting. We curate the first multi-illumination event-instruction corpus for MLLMs, with 2,241 event-RGB samples (around 6 QA pairs each) across diverse scenes and 17 brightness rates (0.05x - 20x), plus an instruct-following benchmark for reasoning, counting, and fine-grained recognition under extreme lighting. Experiments show that Event-MLLM markedly outperforms general-purpose, illumination-adaptive, and event-only baselines, setting a new state of the art in robust multimodal perception and reasoning under challenging illumination.
Existing 3D point tracking methods mostly rely on heuristic designs or scene reconstruction, which incurs significant computational overhead and makes it difficult to meet the demands of real-time applications. To address this problem, in this work, we present a novel spatial tracker that leverages a feed-forward visual geometry transformer to predict the trajectories of arbitrary query points from monocular videos in real time. Specifically, we employ a query initialization mechanism to maintain and update a global feature vector and a set of frame-level feature vectors for each query point. Then, we propose a new spatial tracking framework, which consists of a visual geometry transformer backbone, a global embedding branch, a frame-level embedding branch, and a tracking head. The key innovation lies in the dual-branch embedding design, where the global embedding branch integrates geometry-grounded features of the entire video into global query features to optimize track information across the entire sequence and the frame-level branch combines geometry-grounded features of each respective frame into frame-level query features to refine fine-grained track coordinate predictions. Furthermore, to facilitate collaboration between the global branch and the frame-level branch, we introduce an interaction module which enables unidirectional or bidirectional information exchange between the global query features and frame-level query features. Extensive experiments on various point tracking benchmark datasets show that our approach achieves significantly fast spatial tracking speed compared with state-of-the-art methods, while maintaining comparable tracking accuracy.
TIM: Temporal Decoupling with Iterative Mutual-Refinement Model for Longitudinal Radiology Report Generation
PDF ↗Automatic radiology report generation (RRG) aims to translate medical images into diagnostic text, reducing radiologists' workload and standardizing clinical documentation. Nonetheless, existing approaches mainly focus on single-time point analysis and fail to capture temporal disease evolution across longitudinal examinations. While recent longitudinal RRG (LRRG) approaches incorporate historical data, they often combine images from different time points within a single representation space, leading to blurred semantics and inconsistent temporal reasoning. In this work, we propose a Temporal Decoupling with Iterative MutualRefinement Model (TIM), a two-stage framework that explicitly decouples spatial pathology from temporal progression and iteratively refines reports through mutual feedback. Stage I performs temporal-decoupled representation learning, separating temporal evolution patterns from disease-specific features and generating radiology reports for both prior and current studies. Stage II introduces a mutual report refinement mechanism that identifies diagnostic inconsistencies within prior reports and iteratively rectifies both prior and current reports through error-sensitive feedback. Experiments on the Longitudinal-MIMIC dataset demonstrate that TIM surpasses existing single-image and longitudinal baselines, achieving new state-of-the-art performance across both language and clinical metrics. Code is available at https://github.com/yihengd/TIM.