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Maoqi Liu, Quan Fang, Yuhao Wu, Can Zhao, Yang Yang, Kaiquan Cai

Accurate interpretation of Notices To Airmen (NOTAMs) is critical for aviation safety, yet their condensed and cryptic language poses significant challenges to both manual and automated processing. Existing automated systems are typically limited to "Shallow Parsing," failing to extract the actionable intelligence needed for operational decisions. We formalize the complete interpretation task as "Deep Parsing," a dual-reasoning challenge requiring both dynamic knowledge grounding (linking the NOTAM to evolving real-world aeronautical data) and schema-based inference (applying static domain rules to deduce operational status). To tackle this challenge, we propose NOTAM-Evolve, a self-evolving framework that enables a Large Language Model (LLM) to autonomously master complex NOTAM interpretation. Leveraging a knowledge graph-enhanced retrieval module for data grounding, the framework introduces a crucial closed-loop learning process where the LLM progressively improves from its own outputs, minimizing the need for extensive human-annotated reasoning traces. In conjunction with this framework, we introduce a new benchmark dataset of 10,000 expert-annotated NOTAMs. Our experiments demonstrate that NOTAM-Evolve achieves a 30.4% absolute accuracy improvement over the base LLM, establishing a new state-of-the-art on the task of structured NOTAM interpretation.

Chaohu Liu, Haoyu Cao, YongXiang Hua, Linli Xu

Multimodal table understanding, which aims for a comprehensive grasp of table content by integrating cellular text, tabular structure, and visual presentation, remains a core yet challenging area of research. We identify that the structural complexity of a table, quantifiable by intrinsic properties such as the ratio of merged cells and the total number of cells, presents a significant obstacle for existing models. Our empirical analysis reveals that the performance of leading Multimodal Large Language Models (MLLMs) deteriorates markedly as table complexity increases, exposing a critical vulnerability in their ability to perceive and reason over intricate tabular data. To address this challenge, we propose MM-Table-R1, a model enhanced through difficulty-aware reinforcement learning (RL) post-training strategy. Specifically, we introduce both task-level and data-level curriculum learning. The task-level curriculum is designed to establish a capability ladder, where the model first learns basic perceptual and semantic alignment of table data, and then progresses to acquiring multi-step reasoning capabilities. The data-level curriculum ensures that the model is not exposed to difficult samples prematurely, facilitating a more gradual and effective learning process. Furthermore, we invest considerable effort in constructing a high-quality, large-scale training corpus by curating and processing data from diverse open-source table datasets, ensuring that each instance is paired with an objectively verifiable reward signal. Demonstrating exceptional parameter efficiency, our 3B-parameter model sets a new benchmark by surpassing both established 3B and 7B models, including those specifically designed for table reasoning.

Yue Ling, Peiqi Zhang, Zhenyi Zhang, Peijie Zhou

Single-cell RNA sequencing (scRNA-seq), especially temporally resolved datasets, enables genome-wide profiling of gene expression dynamics at single-cell resolution across discrete time points. However, current technologies provide only sparse, static snapshots of cell states and are inherently influenced by technical noise, complicating the inference and representation of continuous transcriptional dynamics. Although embedding methods can reduce dimensionality and mitigate technical noise, the majority of existing approaches typically treat trajectory inference separately from embedding construction, often neglecting temporal structure. To address this challenge, here we introduce CellStream, a novel deep learning framework that jointly learns embedding and cellular dynamics from single-cell snapshots data by integrating an autoencoder with unbalanced dynamical optimal transport. Compared to existing methods, CellStream generates dynamics-informed embeddings that robustly capture temporal developmental processes while maintaining high consistency with the underlying data manifold. We demonstrate CellStream’s effectiveness on both simulated datasets and real scRNA-seq data, including spatial transcriptomics. Our experiments indicate significant quantitative improvements over state-of-the-art methods in representing cellular trajectories with enhanced temporal coherence and reduced noise sensitivity. Overall, CellStream provides a new tool for learning and representing continuous streams from the noisy, static snapshots of single-cell gene expression.

Yueqing Liang, Liangwei Yang, Chen Wang, Congying Xia, Rui Meng, Xiongxiao Xu, Haoran Wang, Ali Payani, Kai Shu

Large Language Models (LLMs) have achieved significant advances in natural language processing, yet their potential for high-stake political decision-making remains largely unexplored. This paper addresses the gap by focusing on the application of LLMs to the United Nations (UN) decision-making process, where the stakes are particularly high and political decisions can have far-reaching consequences. We introduce a novel dataset comprising publicly available UN Security Council (UNSC) records from 1994 to 2024, including draft resolutions, voting records, and diplomatic speeches. Using this dataset, we propose the United Nations Benchmark (UNBench), the first comprehensive benchmark designed to evaluate LLMs across four interconnected political science tasks: co-penholder judgment, representative voting simulation, draft adoption prediction, and representative statement generation. These tasks span the three stages of the UN decision-making process—drafting, voting, and discussing—and aim to assess LLMs' ability to understand and simulate political dynamics. Our experimental analysis demonstrates the potential and challenges of applying LLMs in this domain, providing insights into their strengths and limitations in political science. To the best of our knowledge, this is the first benchmark to systematically evaluate LLMs in UN decision-making, contributing to the growing intersection of AI and political science.

Ziwei Li, Shuzi Niu, Tao Yuan, Huiyuan Li, Wenjia Wu

Fill-ins are new nonzero elements in the summation of the upper and lower triangular factors generated during LU factorization. For large sparse matrices, they will increase the memory usage and computational time, and be reduced through proper row or column arrangement, namely matrix reordering. Finding a row or column permutation with the minimal fill-ins is NP-hard, and surrogate objectives are designed to derive fill-in reduction permutations or learn a reordering function. However, there is no theoretical guarantee between the golden criterion and these surrogate objectives. Here we propose to learn a reordering network by minimizing l1 norm of triangular factors of the reordered matrix to approximate the exact number of fill-ins. The reordering network utilizes a graph encoder to predict row or column node scores. For inference, it is easy and fast to derive the permutation from sorting algorithms for matrices. For gradient based optimization, there is a large gap between the predicted node scores and resultant triangular factors in the optimization objective. To bridge the gap, we first design two reparameterization techniques to obtain the permutation matrix from node scores. The matrix is reordered by multiplying the permutation matrix. Then we introduce the factorization process into the objective function to arrive at target triangular factors. The overall objective function is optimized with the alternating direction method of multipliers and proximal gradient descent. Experimental results on benchmark sparse matrix collection SuiteSparse show the fill-in and LU factorization time reduction of our proposed method is 0.2% and 17.8% compared with state-of-the-art baselines.

Yuanheng Li, Zhuoyang Chen, Xiaoyun Liu, Yuhao Wang, Mingwei Liu, Yang Shi, Kaifeng Huang, Shengjie Zhao

As large language models (LLMs) become increasingly capable, concerns over the unauthorized use of copyrighted and licensed content in their training data have grown, especially in the context of code. Open-source code, often protected by open source licenses (e.g, GPL), poses legal and ethical challenges when used in pretraining. Detecting whether specific code samples were included in LLM training data is thus critical for transparency, accountability, and copyright compliance. We propose SynPrune, a syntax-pruned membership inference attack method tailored for code. Unlike prior MIA approaches that treat code as plain text, SynPrune leverages the structured and rule-governed nature of programming languages. Specifically, it identifies and excludes consequent tokens that are syntactically required and not reflective of authorship, from attribution when computing membership scores. Experimental results show that SynPrune consistently outperforms the state-of-the-arts. Our method is also robust across varying function lengths and syntax categories.

Yanting Li, Zikang Wang, Jiyue Jiang, Ziqian Lin, Dongchen He, Yuheng Shan, Yanruisheng Shao, Jiayi Li, Xiangyu Shi, Jiuming Wang 等

Inverse Protein Folding (IPF) is a critical subtask in the field of protein design, aiming to engineer amino acid sequences capable of folding correctly into a specified three-dimensional (3D) conformation. Although substantial progress has been achieved in recent years, existing methods generally rely on either backbone coordinates or molecular surface features alone, which restricts their ability to fully capture the complex chemical and geometric constraints necessary for precise sequence prediction. To address this limitation, we present DS-ProGen, a dual-structure deep language model for functional protein design, which integrates both backbone geometry and surface-level representations. By incorporating backbone coordinates as well as surface chemical and geometric descriptors into a next-amino-acid prediction paradigm, DS-ProGen is able to generate functionally relevant and structurally stable sequences while satisfying both global and local conformational constraints. On the PRIDE dataset, DS-ProGen attains the current state-of-the-art recovery rate of 61.47%, demonstrating the synergistic advantage of multi-modal structural encoding in protein design. Furthermore, DS-ProGen excels in predicting interactions with a variety of biological partners, including ligands, ions, and RNA, confirming its robust functional retention capabilities.

Xuyang Li, Jianwu Fang, Lin Li, Boyuan Chen, Guangliang Li, Jianru Xue

Recent advancements in multi-robot navigation have explored methods that combine Large Language Models (LLMs) for tasks like scene understanding or high-level decision-making. However, these approaches face challenges with high inference latency and potential hallucinations. To address these challenges, we propose a knowledge-driven Reinforcement Learning (RL) framework, GUIDER, that utilizes an LLM in two different offline roles. First, we leverage the LLM as an offline knowledge source. Its expertise is distilled into a compact model, which is applied only when the RL agent is uncertain about its own value estimates and the model itself is confident in its prediction. Additionally, we utilize the LLM as an offline semantic engine. This process translates the LLM's high-level understanding of situational risk into a dynamic adjustment of the RL agent's behavioral style, evolving a function that optimally balances conservative and aggressive actions. We conduct extensive experiments in both terrestrial and maritime settings. Across all maritime scenarios (3–12 robots), GUIDER improves the task success rate and reduces the collision rate significantly compared to the state-of-the-art RL-based multi-robot navigation methods.

Tingting Li, Ziming Zhao, Jianwei Yin

Fidelity estimation is a critical yet resource-intensive step in testing quantum programs on noisy intermediate-scale quantum (NISQ) devices, where the required number of measurements is difficult to predefine due to hardware noise, device heterogeneity, and transpilation-induced circuit transformations. We present QuFid, an adaptive and noise-aware framework that determines measurement budgets online by leveraging circuit structure and runtime statistical feedback. QuFid models a quantum program as a directed acyclic graph (DAG) and employs a control-flow-aware random walk to characterize noise propagation along gate dependencies. Backend-specific effects are captured via transpilation-induced structural deformation metrics, which are integrated into the random-walk formulation to induce a noise-propagation operator. Circuit complexity is then quantified through the spectral characteristics of this operator, providing a principled and lightweight basis for adaptive measurement planning. Experiments on 18 quantum benchmarks executed on IBM Quantum backends show that QuFid significantly reduces measurement cost compared to fixed-shot and learning-based baselines, while consistently maintaining acceptable fidelity bias.

Taotao Li, Yiyang Li, Zhenyu Wen, Jiahao Lin, Jinhao Wan, Jie Su, Cong Wang, Zhen Hong

In recent years, RF fingerprinting (RFF) has emerged as a promising technology for wireless device authentication. However, temporal variations in device load and temperature, along with channel effects, lead to inconsistencies in RFF distributions between training and testing phases. As a result, deep learning (DL)-based recognition models often suffer from degraded performance. To address this problem, we propose the first test-time-adaptation (TTA) approach to improve the domain generalization ability of RFF recognition models. We first analyze the causes of time-varying RFF distribution shifts, such as carrier frequency offset (CFO), and develop a physical impairment-based data augmentation strategy. Based on this, we further propose a physically information-aware prototype to guide the model for TTA. Our method requires no model retraining or labeled test samples, and is a lightweight, nonparametric solution. Finally, our approach is extensively evaluated using mobile phones with the IEEE 802.11 orthogonal frequency division multiplexing (OFDM) system, which demonstrates that our scheme can effectively improve RFF average recognition performance by about 7.8%.

Songlin Li, Guofeng Yu, Zhiqing Guo, Yunfeng Diao, Dan Ma, Gaobo Yang

Deep learning-based image manipulation localization (IML) methods have achieved remarkable performance in recent years, but typically rely on large-scale pixel-level annotated datasets. To address the challenge of acquiring high-quality annotations, some recent weakly supervised methods utilize image-level labels to segment manipulated regions. However, the performance is still limited due to insufficient supervision signals. In this study, we explore a form of weak supervision that improves the annotation efficiency and detection performance, namely scribble annotation supervision. We re-annotated mainstream IML datasets with scribble labels and propose the first scribble-based IML (Sc-IML) dataset. Additionally, we propose the first scribble-based weakly supervised IML framework. Specifically, we employ self-supervised training with a structural consistency loss to encourage the model to produce consistent predictions under multi-scale and augmented inputs. In addition, we propose a prior-aware feature modulation module (PFMM) that adaptively integrates prior information from both manipulated and authentic regions for dynamic feature adjustment, further enhancing feature discriminability and prediction consistency in complex scenes. We also propose a gated adaptive fusion module (GAFM) that utilizes gating mechanisms to regulate information flow during feature fusion, guiding the model toward emphasizing potential tampered regions. Finally, we propose a confidence-aware entropy minimization loss. This loss dynamically regularizes predictions in weakly annotated or unlabeled regions based on model uncertainty, effectively suppressing unreliable predictions. Experimental results show that our method outperforms existing fully supervised approaches in terms of average performance both in-distribution and out-of-distribution.

Siyuan Li, Kai Yu, Anna Wang, Zicheng Liu, Chang Yu, Jingbo Zhou, Qirong Yang, Yucheng Guo, Xiaoming Zhang, Stan Z. Li

Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit. Relying on either four primitive bases or independently designed DNA tokenizers, existing approaches with naive masked language modeling pre-training often fail to adapt to the varying complexities of genomic sequences. Leveraging Token Merging techniques, this paper introduces a hierarchical architecture that jointly optimizes a dynamic genomic tokenizer and latent Transformers with context-aware pre-training tasks. As for network structures, the tokenization module automatically chunks adjacent bases into words by stacking multiple layers of the differentiable token merging blocks with local-window constraints, then a Latent Encoder captures the global context of these merged words by full-attention blocks. Symmetrically employing a Latent Decoder and a Local Decoder, MergeDNA learns with two pre-training tasks: Merged Token Reconstruction simultaneously trains the dynamic tokenization module and adaptively filters important tokens, while Adaptive Masked Token Modeling learns to predict these filtered tokens to capture informative contents. Extensive experiments show that MergeDNA achieves superior performance on three popular DNA benchmarks and several multi-omics tasks with fine-tuning or zero-shot evaluation, outperforming typical tokenization methods and large-scale DNA foundation models.

Shunfan Li, Jiangkai Long, Xin Zou, Chang Tang, Yuanyuan Liu, Xiao He, Xuesong Yan

Protein-Ligand Affinity (PLA) prediction quantifies the interaction strength to guide rational drug design. Existing approaches typically analyze interaction at a single granularity and overlook tightly coupled relationships between protein and ligand in both structure and functionality, consequently yielding suboptimal representations, leading to significant performance drops in real-world scenarios. To address this problem, we propose PLA-MGRA, a minimalist and effective PLA prediction framework. Specifically, PLA-MGRA captures both fine-grained atomic details and coarse grained functional semantics within the 3D structure of protein–ligand complexes, through multi-granularity learning. To further parse the coupled protein–ligand relationships, we design relation-aware learning to enhance the binding nature of representations. Extensive experiments demonstrate that our method achieves state-of-the-art performance on multiple protein–ligand affinity prediction benchmarks, while also offering generalizability and interpretability.

Shen Li, Li Huang, Shaoxiong Zhan, Weifeng Sun, Tao Yin, Zhongxin Liu, Meng Yan

Large language models (LLMs) exhibit strong generative capabilities and have shown great potential in code generation. Existing chain-of-thought (CoT) prompting methods enhance model reasoning by eliciting intermediate steps, but suffer from two major limitations: First, their uniform application tends to induce overthinking on simple tasks. Second, they lack intention abstraction in code generation, such as explicitly modeling core algorithmic design and efficiency, leading models to focus on surface-level structures while neglecting the global problem objective. Inspired by the cognitive economy principle of engaging structured reasoning only when necessary to conserve cognitive resources, we propose RoutingGen, a novel difficulty-aware routing framework that dynamically adapts prompting strategies for code generation. For simple tasks, it adopts few-shot prompting; for more complex ones, it invokes a structured reasoning strategy, termed Intention Chain-of-Thought (ICoT), which we introduce to guide the model in capturing task intention, such as the core algorithmic logic and its time complexity. Experiments across three models and six standard code generation benchmarks show that RoutingGen achieves state-of-the-art performance in most settings, while reducing total token usage by 46.37% on average across settings. Furthermore, ICoT outperforms six existing prompting baselines on challenging benchmarks.

Ruikun Li, Jiazhen Liu, Huandong Wang, Qingmin Liao, Yong Li

Modeling stochastic dynamics from discrete observations is a key interdisciplinary challenge. Existing methods often fail to estimate the continuous evolution of probability densities from trajectories or face the curse of dimensionality. To address these limitations, we presents a novel paradigm: modeling dynamics directly in the weight space of a neural network by projecting the evolving probability distribution. We first theoretically establish the connection between dynamic optimal transport in measure space and an equivalent energy functional in weight space. Subsequently, we design WeightFlow, which constructs the neural network weights into a graph and learns its evolution via a graph controlled differential equation. Experiments on interdisciplinary datasets show that WeightFlow improves performance by an average of 43.02\% over state-of-the-art methods, providing an effective and scalable solution for modeling high-dimensional stochastic dynamics.

Nuo Li, Yuan Xiong, Chengliang Liu, Jie Wen, Chao Huang

The increasing prominence of short video platforms has positioned them as a primary channel for public awareness of current events, while also facilitating the widespread dissemination of fake news, thus highlighting the critical need for automated detection technologies. In contrast to fake news confined to text and images, short video news encompasses multiple modalities and extensive information, presenting heightened challenges. Most existing research emphasizes the analysis of news content or user comments alone, while overlooking the crucial role of publishers, leading to poor model performance when handling fake news lacking obvious false signals. Therefore, we propose a Publisher Profiling Module to identify new false signals. To enable a more comprehensive detection of misinformation, we design a Multi-View Aggregation (MVA) model, simultaneously evaluating news from three distinct perspectives: sentiment analysis, content understanding, and publisher profiling. Late fusion is applied at the decision level to leverage the complementary strengths of these perspectives, addressing the limitations of single-view methods. Our experiments conducted on the FakeSV and FVC datasets demonstrate the superior performance of the proposed method.

Mengran Li, Zelin Zang, Wenbin Xing, Junzhou Chen, Ronghui Zhang, Jiebo Luo, Stan Z. Li

Understanding how chemical perturbations propagate through biological systems is essential for robust molecular property prediction. While most existing methods focus on chemical structures alone, recent advances highlight the crucial role of cellular responses such as morphology and gene expression in shaping drug effects. However, current cell-aware approaches face two key limitations: (1) modality incompleteness in external biological data, and (2) insufficient modeling of hierarchical dependencies across molecular, cellular, and genomic levels. We propose CHMR (Cell-aware Hierarchical Multi-Modal Representations), a robust framework that jointly models local-global dependencies between molecules and cellular responses and captures latent biological hierarchies via a novel tree-structured vector quantization module. Evaluated on public benchmarks spanning 696 tasks, CHMR outperforms state-of-the-art baselines, yielding average improvements of 3.6% on classification and 17.2% on regression tasks. These results demonstrate the advantage of hierarchy-aware, multi-modal learning for reliable and biologically grounded molecular representations, offering a generalizable framework for integrative biomedical modeling.

Harrison H Li, Medhanie Irgau, Nabil Janmohamed, Karen Solveig Rieckmann, David B. Lobell

Precise estimation and uncertainty quantification for average crop yields are critical for agricultural monitoring and decision making. Existing data collection methods, such as crop cuts in randomly sampled fields at harvest time, are relatively time-consuming. Thus, we propose an approach based on prediction-powered inference (PPI) to supplement these crop cuts with less time-consuming field photos. After training a computer vision model to predict the ground truth crop cut yields from the photos, we learn a "control function" that recalibrates these predictions with the spatial coordinates of each field. This enables fields with photos but not crop cuts to be leveraged to improve the precision of zone-wide average yield estimates. Our control function is learned by training on a dataset of nearly 20,000 real crop cuts and photos of rice and maize fields in sub-Saharan Africa. To improve precision, we pool training observations across different zones within the same first-level subdivision of each country. Our final PPI-based point estimates of the average yield are provably asymptotically unbiased and cannot increase the asymptotic variance beyond that of the natural baseline estimator --- the sample average of the crop cuts --- as the number of fields grows. We also propose a novel bias-corrected and accelerated (BCa) bootstrap to construct accompanying confidence intervals. Even in zones with as few as 20 fields, the point estimates show significant empirical improvement over the baseline, increasing the effective sample size by as much as 73% for rice and by 12-23% for maize. The confidence intervals are accordingly shorter at minimal cost to empirical finite-sample coverage. This demonstrates the potential for relatively low-cost images to make area-based crop insurance more affordable and thus spur investment into sustainable agricultural practices.

Hao Li, Andrey Bogdanov

Metasurfaces are ultrathin, engineered materials composed of nanostructures that manipulate light in ways unattainable by natural materials. Recent advances have leveraged computational optimization, machine learning, and deep learning to automate their design. However, existing approaches exhibit two fundamental limitations: (1) they often restrict the model to generating only a subset of design parameters, and (2) they rely on heavily downsampled spectral targets, which compromises both the novelty and accuracy of the resulting structures. The core challenge lies in developing a generative model capable of exploring a large, unconstrained design space while precisely capturing the intricate physical relationships between material parameters and their high-resolution spectral responses. In this paper, we introduce MetaDiT, a novel framework for high-fidelity metasurface design that addresses these limitations. Our approach leverages a robust spectrum encoder pretrained with contrastive learning, providing strong conditional guidance to a Diffusion Transformer-based backbone. Experiments demonstrate that MetaDiT outperforms existing baselines in spectral accuracy, we further validate our method through extensive ablation studies.

Haitao Li, Ziyu Li, Yiheng Mao, Ziyi Liu, Zhoujian Sun, Zhengxing Huang

The advent of multimodal large language models (MLLMs) has sparked interest in their application to electrocardiogram (ECG) analysis. However, existing ECG-focused MLLMs primarily focus on report generation tasks, often limited to single 12-lead, short-duration (10s) ECG inputs, thereby underutilizing the potential of MLLMs. To this end, we aim to develop a MLLM for ECG analysis that supports a broader range of tasks and more flexible ECG inputs. However, existing ECG-QA datasets are often monotonous. To address this gap, we first constructed the anyECG dataset, which encompasses a wide variety of tasks, including report generation, abnormal waveform localization, and open-ended question answering. In addition to standard hospital ECGs, we introduced long-duration reduced-lead ECGs for home environments and multiple ECG comparison scenarios commonly encountered in clinical practice. Furthermore, we propose the anyECG-chat model, which supports dynamic-length ECG inputs and multiple ECG inputs. We trained the model using a three-stage curriculum training recipe with the anyECG dataset. A comprehensive evaluation was conducted, demonstrating that anyECG-chat is capable of supporting various practical application scenarios, including not only common report generation tasks but also abnormal waveform localization for long-duration reduced-lead ECGs in home environments and comprehensive comparative analysis of multiple ECGs.