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Applications · Health / Medicine

Aofei Chang, Le Huang, Alex Boyd, parminder bhatia, Taha Kass-Hout, Fenglong Ma, Cao Xiao

Medical large vision-language models (Med-LVLMs) have recently achieved remarkable progress in vision–language comprehension and medical image segmentation. However, existing models still struggle to unify these two capabilities, which is essential for achieving clinically reasoning that connects visual findings with semantic interpretation. We present MedSIGHT, a unified framework that equips Med-LVLMs with structured, pixel-level understanding for grounded visual comprehension. MedSIGHT introduces a novel Region Perceiver module that produces region-centric tokens, encoding spatial information directly into representation space of the language model. We further propose a medical region codebook into the LLM vocabulary, allowing the model to generate discrete region codes as symbolic representations of anatomical and pathological regions. These codes are decoded through the Region Perceiver to reconstruct segmentation mask, achieving end-to-end spatial grounding. Lastly, MedSIGHT combines Region Perceiver, Codebook and LLM using our proposed progressive training strategy to gradually aligns these modules stably. Trained on only 72K multimodal instruction pairs, MedSIGHT achieves state-of-the-art performance across diverse imaging modalities on both medical comprehension and segmentation tasks.

Applications · Computer Vision

Chenming Zhu, Peizhou Cao, Jingli Lin, Wenbo Hu, Yunlong Ran, Tai Wang, Jiangmiao Pang, Xihui Liu

Human spatial understanding arises from jointly perceiving geometry and semantics, enabling consistent object identification and localization across viewpoints and time. Current video segmentation models depend on explicit object appearance memory banks for instance tracking, yet they remain vulnerable to large viewpoint changes and long-term occlusions. Leveraging the spatial consistency afforded by modern feed-forward 3D reconstruction models, we propose the Geometry Grounded Tracking Anything Model (G$^2$TAM), a unified framework for promptable instance tracking in 3D using only unordered RGB images or videos. G$^2$TAM employs spatially aligned geometric representations as implicit memory, ensuring stable instance identity and localization across frames and views. At its core is a cross-modal spatial encoder that integrates visual and textual prompts into a shared geometric space, enabling end-to-end spatial reconstruction and instance-consistent mask prediction. To support training and evaluation, we construct InsTrack, a large-scale dataset with a dedicated validation split for benchmarking. Extensive experiments show that G$^2$TAM delivers strong cross-view consistency, promptable instance spatial tracking, video object segmentation, and spatial reconstruction, establishing a foundation for interactive, geometry-grounded spatial reasoning.

Applications · Computer Vision

Shiyan Tong, Jinxia Zhang, Zhiyuan Wang, Hao Tian, YingYing Wang, Kanjian Zhang, Haikun Wei

Recent advances in zero-shot referring image segmentation (RIS), driven by foundation models such as SAM and CLIP, have improved cross-modal alignment between visual regions and natural language expressions. Nevertheless, selecting the correct segmentation proposal remains challenging, as existing methods typically rely on independent proposal scoring and lack contextual reasoning among visually similar candidates. To address this limitation, we propose RefChess, a training-free framework that reformulates proposal selection as a decision-making problem under contextual perturbations rather than a single-step ranking task. RefChess models each proposal as a candidate chess move and applies Monte-Carlo Tree Search to evaluate its robustness by simulating interactions with competing regions, guided by a stability-aware reward that integrates language decomposition, vision–language similarity, object-centric cues, and spatial guidance signals. Experimental results on standard RIS benchmarks indicate that this decision-centric formulation leads to consistent improvements in robustness and referring segmentation performance. Code is available at \url{anonymous URL}.

Applications · Computer Vision

Yikai Wang, Chenjie Cao, Ke Fan, Qiaole Dong, Yifan Li, Xiangyang Xue, Yanwei Fu

Current image manipulation primarily centers on static manipulation, such as replacing specific regions within an image or altering its overall style. In this paper, we introduce an innovative dynamic manipulation task, subject repositioning. This task involves relocating a user-specified subject to a desired position while preserving the image's fidelity. Our research reveals that the fundamental sub-tasks of subject repositioning, which include filling the void left by the repositioned subject, reconstructing obscured portions of the subject and blending the subject to be consistent with surrounding areas, can be effectively reformulated as a unified, prompt-guided inpainting task. Consequently, we can employ a single diffusion generative model to address these sub-tasks using various task prompts learned through our proposed task inversion technique. Additionally, we integrate pre-processing and post-processing techniques to further enhance the quality of subject repositioning. These elements together form our SEgment-gEnerate-and-bLEnd (SEELE) framework. To assess SEELE's effectiveness in subject repositioning, we assemble a real-world subject repositioning dataset called ReS. Results of SEELE on ReS demonstrate its efficacy. Code and ReS dataset are available at https://yikai-wang.github.io/seele/.

Applications · Chemistry, Physics, and Earth Sciences

Jiwoong Kim, Jongwon Lee, Jungwoo Park, Sungwoo Park

We present a Lie-algebraic approach to model Koopman dynamics that integrates algebraic structure with computational scalability. The proposed formulation constrains the neural generators to evolve within prescribed Lie subalgebras and constructs finite-time flows through a neural Magnus expansion construction, thereby maintaining consistency with the associated Lie-group composition over each time segment. To address the computational burden inherent in sequential propagation, we exploit the associativity of Lie-group compositions and construct segmentwise propagators via a prefix-scan algorithm, which reduces the depth of temporal composition from linear to logarithmic. Consequently, the framework enables accurate long-horizon prediction while improving computational efficiency, and provides a principled foundation for scalable Koopman operator learning for nonlinear systems.

Applications · Robotics

Chenyu Hui, Xiaodi Huang, Siyu Xu, Yunke Wang, Shan You, Fei Wang, Tao Huang, Chang Xu

Vision-language-action (VLA) models typically rely on large-scale real-world videos, whereas simulated data, despite being inexpensive and highly parallelizable to collect, often suffers from a substantial visual domain gap and limited environmental diversity, resulting in weak real-world generalization. We present an efficient video augmentation framework that converts simulated VLA videos into realistic training videos while preserving task semantics and action trajectories. Our pipeline extracts structured conditions from simulation via video semantic segmentation and video captioning, rewrites captions to diversify environments, and uses a conditional video transfer model to synthesize realistic videos. To make augmentation practical at scale, we introduce a diffusion feature-reuse mechanism that reuses video tokens across adjacent timesteps to accelerate generation, and a coreset sampling strategy that identifies a compact, non-redundant subset for augmentation under limited computation. Extensive experiments on RobotWin 2.0, LIBERO, LIBERO-Plus, and a real robotic platform demonstrate consistent improvements in both task performance and sim-to-real generalization. For example, our method improves RDT-1B by 8% on RobotWin 2.0, and boosts $\pi_0$ by 5.1% on the more challenging LIBERO-Plus benchmark. Code is released in supplementary material.

Deep Learning · Large Language Models

Xiangyu Zeng, Qi Xu, Yunke Wang, Chang Xu

Long-context language modeling is commonly framed as a scalability challenge of token-level attention, yet local-to-global information structuring remains largely implicit in existing approaches. Drawing on cognitive theories of discourse comprehension, we propose HiCI (Hierarchical Construction--Integration), a hierarchical attention module that constructs segment-level representations, integrates them into a shared global context, and broadcasts both to condition segment-level attention. We validate HiCI through parameter-efficient adaptation of LLaMA-2 with only $\sim$5.5\% additional parameters, extending context from 4K to 100K tokens (7B) and 64K tokens (13B). Across language modeling, retrieval, and instruction-following benchmarks, HiCI yields consistent improvements over strong baselines, including matching proprietary models on topic retrieval and surpassing GPT-3.5-Turbo-16K on code comprehension. These results demonstrate the effectiveness of explicit hierarchical structuring as an inductive bias for long-context modeling.

Applications · Computer Vision

Rui Zhao, Wenrui Li, Lin Zhu, Yajing Zheng, Weisi Lin

Deep visual features are increasingly used as the interface in vision systems, motivating the need to describe feature characteristics and control feature quality for machine perception. Just-noticeable difference (JND) characterizes the maximum imperceptible distortion for images under human or machine vision. Extending it to deep visual features naturally meets the above demand by providing a task-aligned tolerance boundary in feature space, offering a practical reference for controlling feature quality under constrained resources. We propose FeatJND, a task-aligned JND formulation that predicts the maximum tolerable per-feature perturbation map while preserving downstream task performance. We propose a FeatJND estimator at standardized split points and validate it across image classification, detection, and instance segmentation. Under matched distortion strength, FeatJND-based distortions consistently preserve higher task performance than unstructured Gaussian perturbations, and attribution visualizations suggest FeatJND can suppress non-critical feature regions. As an application, we further apply FeatJND to token-wise dynamic quantization and show that FeatJND-guided step-size allocation yields clear gains over random step-size permutation and global uniform step size under the same noise budget. Our code will be released after publication.

Applications · Computer Vision

Jiankang Wang, Dingding Jia, Zhoushuopeng, Xuan Wang

Open-Vocabulary Segmentation(OVS) aims to achieve pixel-level semantic recognition from arbitrary text queries. Existing large-scale visual-linguistic models, such as CLIP, perform well in zero-shot generalization, but their image-level training objectives and real-valued cross-modal alignment mix amplitude and phase information, limiting fine-grained segmentation and often causing blurred boundaries and fragmented structures. Inspired by the ability of electromagnetic wave phase to control interference independently of amplitude, we propose PhaseAlign, an OVS framework based on Complex Phase Alignment (CPA). CPA explicitly decouples the magnitude and phase of visual and textual embeddings in the complex domain, refining effective features for stable cross-modal alignment. To further enhance structural awareness, we introduce spatial-aware cross-modal projection, which models local neighborhood relations via multi-scale spatial contrast normalization, and attention-guided affinity modeling, which leverages pre-trained ViT self-attention to propagate category activations, improving boundary clarity and region integrity. Experiments show that PhaseAlign achieves state-of-the-art performance on multiple OVS benchmarks.

Applications · Computer Vision

Luke Miller, Yugyung Lee

Segmenting small and sparse structures in large-scale images is fundamentally constrained by pixel-level, lattice-bound computation and extreme class imbalance--dense, full-resolution inference scales poorly and forces most pipelines to rely on fixed regionization or downsampling, coupling computational cost to image resolution and attenuating boundary evidence precisely where minority structures are most informative. We introduce **SEMIR** (*Semantic Minor-Induced Representation Learning*), a representation framework that decouples inference from the native grid by learning a task-adapted inference space. **SEMIR** transforms the underlying grid graph into a compact, boundary-aligned graph minor through parameterized edge contraction, node deletion, and edge deletion, while preserving an exact lifting map from minor predictions to lattice labels. Minor construction is formalized as a few-shot optimization problem that replaces hand-tuned preprocessing with a *boundary-alignment objective*: minor parameters are learned by maximizing agreement between predicted boundary elements and class-agnostic semantic edges under a *boundary Dice criterion*, and the induced minor is annotated with scale- and rotation-robust geometric and intensity descriptors and supports efficient region-level inference via message passing on a graph neural network (GNN) with relational edge features. We benchmark **SEMIR** on three tumor segmentation datasets—**BraTS2021**, **KiTS2023**, and **LiTS2017**—where targets exhibit high structural variability and distributional uncertainty, providing a stringent testbed for *structure-adaptive inference*. **SEMIR** yields consistent improvements in *minority-structure Dice* at practical runtime, positioning *minor-induced representations* as a principled alternative to pixel-centric segmentation in challenging, high-variability visual domains.

Deep Learning · Generative Models and Autoencoders

Bin Zang, Rengan Xie, Xiaoliang Luo, Zhiyuan Fang, Shi Li, Lvchun Wang, Wei Yu, Yi Zhao, Yuchi Huo, Tian Xie 等

Recently, a line of works can generate impressive 3D objects from a single image, but they are limited by restricted representation resolution, making them unsuitable for 3D scene generation. In this work, we introduce \name, a novel method for high-quality 3D scene generation based on hierarchical voxel enhancement framework. Specifically, given a single scene image as input, we first produce a coarse initial scene, then introduce image segmentation and attention-based retrieval to align 2D image components with 3D scene components. Subsequently, we organize these scene relations into a hierarchical component tree, where nodes closer to the leaves denote finer-grained components. Finally, we propose a voxel super-resolution model that generates refined voxels for the target instance while maintaining strong consistency with the coarse voxels. Equipped with this model, we perform coarse-to-fine hierarchical super-resolution on images and voxels for each component, producing a high-resolution and high-quality 3D scene. Extensive experiments demonstrate that our method significantly outperforms previous approaches, achieving state-of-the-art performance.

Applications · Language, Speech and Dialog

Clara Meister, Ahmetcan Yavuz, Pietro Lesci, Tiago Pimentel

Language Identification (LID) is an important component of many multilingual natural language processing pipelines, where it facilitates corpus curation, training data analysis, and cross-lingual evaluation of large language models. Despite near-perfect performance on high-resource languages, existing systems remain brittle in low-resource and closely related language settings. We introduce a simple and efficient LID method based on the probabilistic framing, parameter estimation technique and inference strategy of the UnigramLM tokenization algorithm. In short, we learn language-conditional unigram distributions over a shared tokenizer vocabulary but treat segmentation as a language-specific phenomenon. Our formulation is data- and compute-efficient, supports incremental addition of new languages without retraining existing models, and can naturally be integrated into existing language model tokenization pipelines. Empirical evaluations against widely used baselines, including fastText, GlotLID-M, and CLD3, show that UniLID achieves competitive performance on standard benchmarks, substantially improves sample efficiency in low-resource settings--surpassing 70% accuracy with as few as five labeled samples per language---and delivers large gains on fine-grained dialect identification.

General Machine Learning · Transfer, Multitask and Meta-learning

Hongyou Zhou, Zihan Ye, Ling Shao, Marc Toussaint

Despite strong zero-shot performance, SAM is unreliable under domain shift due to Mask-level Confidence Confusion (MCC), where a single IoU-based mask score fails to reflect pixel-wise reliability near boundaries. Motivated by the contrast between texture-biased shortcuts in neural networks and shape-centric processing in human vision, we model out-of-domain variation as appearance shifts and non-rigid deformations that jointly stress calibration. We propose Segment Anything with Robust Uncertainty-Accuracy Correlation (RUAC) for robust pixel-wise uncertainty estimation under appearance and deformation shifts. RUAC adds a lightweight uncertainty head, trains it with a collaborative style-deformation attack that jointly perturbs texture and geometry, and applies Uncertainty-Error Alignment to ensure uncertainty consistently highlights erroneous pixels even under adversarial perturbations. Across 23 zero-shot domains, RUAC improves segmentation quality and yields more faithful uncertainty with stronger uncertainty-accuracy correlation.

Applications · Everything Else

Arnav Shah, Junzhe Li, Parsa Idehpour, Adibvafa Fallahpour, Brandon Wang, Sukjun Hwang, BO WANG, Patrick Hsu, Hani Goodarzi, Albert Gu

Genomic foundation models have the potential to decode DNA syntax, yet face a fundamental tradeoff. Standard subword tokenizers fragment biologically meaningful motifs such as codons and regulatory elements, while nucleotide-level models preserve biological coherence but incur prohibitive computational costs for long contexts. We introduce dnaHNet, a state-of-the-art tokenizer-free autoregressive model that segments and models genomic sequences end to end. Using a differentiable dynamic chunking mechanism, dnaHNet compresses raw nucleotides into latent tokens adaptively, balancing compression with predictive accuracy. Pretrained on prokaryotic genomes, dnaHNet outperforms leading architectures including StripedHyena2 in scaling and efficiency. This recursive chunking yields quadratic FLOP reductions, enabling $>3 \times$ inference speedup over Transformers. On zero-shot tasks, dnaHNet achieves superior performance in predicting protein variant fitness and gene essentiality, while automatically discovering hierarchical biological structures without supervision. These results establish dnaHNet as a scalable, interpretable framework for next-generation genomic modeling.

Applications · Everything Else

Arnav Shah, Junzhe Li, Parsa Idehpour, Adibvafa Fallahpour, Brandon Wang, Sukjun Hwang, BO WANG, Patrick Hsu, Hani Goodarzi, Albert Gu

Genomic foundation models have the potential to decode DNA syntax, yet face a fundamental tradeoff. Standard subword tokenizers fragment biologically meaningful motifs such as codons and regulatory elements, while nucleotide-level models preserve biological coherence but incur prohibitive computational costs for long contexts. We introduce dnaHNet, a state-of-the-art tokenizer-free autoregressive model that segments and models genomic sequences end to end. Using a differentiable dynamic chunking mechanism, dnaHNet compresses raw nucleotides into latent tokens adaptively, balancing compression with predictive accuracy. Pretrained on prokaryotic genomes, dnaHNet outperforms leading architectures including StripedHyena2 in scaling and efficiency. This recursive chunking yields quadratic FLOP reductions, enabling $>3 \times$ inference speedup over Transformers. On zero-shot tasks, dnaHNet achieves superior performance in predicting protein variant fitness and gene essentiality, while automatically discovering hierarchical biological structures without supervision. These results establish dnaHNet as a scalable, interpretable framework for next-generation genomic modeling.

General Machine Learning · Scalable Algorithms

Celine Lee, Jing Nathan Yan, Chen Liang, Jiaxin Shi, Yin Zhang, Jeremiah Zhe Liu, Pengcheng Yin, Ed Chi, Fernando Pereira, Derek Cheng 等

Modern language models typically rely on two design choices: subword tokenization and autoregressive (AR) ordering. To achieve more universal modeling, the field is advancing toward byte-level modeling to bypass domain-specific vocabularies and masked diffusion models (MDM) to enable parallel non-sequential generation. Intuitively, the intersection of these paradigms represents a generative ideal: a modality-agnostic system capable of fine-grained any-order generation. However, the computational interaction between these granular representations and non-sequential objectives remains under-explored. In this work, we investigate the viability of this combination through a compute-matched scaling study. We observe a structural dichotomy: AR models on bytes effectively amortize the cost of tokenization, naturally rediscovering sub-word segmentation at scale. In contrast, byte-level MDMs suffer a non-convergent efficiency collapse. We attribute this disparity to the masking objective, which shatters the local contiguity required to resolve sub-word semantics from bytes, whereas AR's stable causal history preserves these essential local dependencies. Our findings inform the community of a critical efficiency tradeoff, suggesting that future modality-agnostic designs should address this context fragility to maintain efficient scaling.

Chu Zhao, Enneng Yang, Yuting Liu, Jianzhe Zhao, Guibing Guo

Test-time reinforcement learning generates multiple candidate answers via repeated rollouts and performs online updates using pseudo-labels constructed by majority voting. To reduce overhead and improve exploration, prior work introduces tree-structured rollouts, which share reasoning prefixes and branch at key nodes to improve sampling efficiency. However, this paradigm still faces two challenges: (1) high-entropy branching can trigger rollout collapse, where the branching budget concentrates on a few trajectories with consecutive high-entropy segments, rapidly reducing the number of effective branches; (2) early pseudo-labels are noisy and biased, which can induce self-reinforcing overfitting, causing the policy to sharpen prematurely and suppress exploration. To address these issues, we propose Entropy–Confidence Hybrid Group Relative Policy Optimization (ECHO). During rollout, ECHO jointly leverages local entropy and group-level confidence to adaptively control branch width, and further introduces online confidence-based pruning to terminate persistently low-confidence branches, avoiding high-entropy traps and mitigating collapse. During policy updates, ECHO employs confidence-adaptive clipping and an entropy–confidence hybrid advantage shaping approach to enhance training robustness and mitigate early-stage bias. Experiments demonstrate that ECHO achieves consistent gains on multiple mathematical and visual reasoning benchmarks, and generalizes more effectively under a limited rollout budget.

Applications · Computer Vision

Sanaullah Chowdhury, Lameya Sabrin

Medical image segmentation requires balancing global context with computational efficiency, where self-attention mechanisms suffer from quadratic $\mathcal{O}((HW)^2 C)$ complexity. We propose S2M-Net, a parameter-efficient architecture (4.7M parameters) that achieves computational savings through Spectral--Spatial Token Mixing (SSTM). SSTM achieves $\mathcal{O}(HWC^2)$ complexity through efficient combination of $\mathcal{O}(HWC \log(HW))$ frequency-domain processing and $\mathcal{O}(HWCd)$ bottlenecked spatial gating ($d{=}16$), exploiting spectral concentration where $>93\%$ of energy is captured by $K{=}32$ low-frequency components ($\sim$0.8\% of the spectrum at $352{\times}352$ resolution). This design avoids self-attention's prohibitive $\mathcal{O}((HW)^2C)$ attention map computations while preserving global receptive fields. To handle geometric diversity, we introduce Morphology-Aware Adaptive Segmentation Loss (MASL), which automatically modulates five loss objectives based on per-sample morphological descriptors (tubularity, compactness, irregularity, and scale). Evaluation across 15 datasets spanning 8 modalities demonstrates competitive performance, obtaining the best performance on 14 of 15 datasets, with statistically significant improvements ($p < 0.0033$, Bonferroni-corrected) on 7 challenging tasks (complex morphology, class imbalance, and multi-class segmentation), and clinically meaningful gains ($0.5$--$1.6\%$ Dice) on 8 mature benchmarks. Notably, S2M-Net achieves $83.43\%$ Dice on EndoVis17 multiclass instrument segmentation ($+8.69\%$ over TransUNet and $+9.14\%$ over the best baseline UMamba at $74.29\%$), while using $12.8{\times}$ fewer parameters (4.7M vs.\ 60M).

Reinforcement Learning · Batch/Offline

Yunpeng Qing, Yixiao Chi, Shuo Chen, Shunyu Liu, Kexuan Zhou, Sixu Lin, Litao Liu, Changqing Zou

Offline Reinforcement Learning (RL) relies on static datasets and often enforces conservative constraints to mitigate out-of-distribution errors, but this inevitably gives rise to learning dataset biases and limited behavioral generalization. Recent Data Augmentation (DA) methods leverage generative models to enrich offline data, yet they mainly operate within a single rollout paradigm and tend to preserve the original trajectory-level connectivity of the dataset. As a result, such methods often introduce local variations and fail to recover connections between distinct behavior patterns. In this paper, we propose Bidirectional Trajectory Diffusion (BiTrajDiff), a novel DA framework that explicitly addresses this limitation. BiTrajDiff decomposes trajectory synthesis into two independent diffusion processes that generate forward-future and backward-history segments conditioned on shared intermediate anchor states. By stitching the generated segments at these anchors, BiTrajDiff can synthesize trajectories that bridge disconnected behavior patterns and recover global trajectory-level connectivity absent from the original data. Extensive experiments on the D4RL benchmark demonstrate that BiTrajDiff consistently outperforms advanced DA methods across a range of offline RL backbones.

Applications · Language, Speech and Dialog

Kai Li, Jintao Cheng, Chang Zeng, Zijun Yan, Helin Wang, Zixiong Su, Bo Zheng, Xiaolin Hu

Query-based universal sound separation is fundamental to intelligent auditory systems, aiming to isolate specific sources from mixtures. Despite recent advances, existing methods continue to suffer from residual interference in complex acoustic scenes. This performance limitation stems largely from a data bottleneck: in-the-wild datasets contain weak labels and severe co-occurrence of events. These flaws induce models to learn spurious correlations between background noise and target categories instead of robust acoustic features. To address this, we propose an automated pipeline that eliminates co-occurrence of events by mining high-purity single-event segments from in-the-wild datasets via a semantically consistent synthesis protocol. Utilizing this pipeline, we constructed *Hive*, a high-quality synthetic dataset comprising 2.4k hours of raw audio. Experimental results demonstrate that, compared with the state-of-the-art model SAM-Audio which was trained on a huge dataset $\sim$500 times larger than Hive, certain open-source models trained on Hive achieve competitive separation accuracy and perceptual quality. Moreover, these models exhibited remarkable zero-shot generalization on out-of-distribution evaluation benchmarks. These findings highlight that prioritizing purity of supervised signals enables significant data efficiency, offering a new paradigm for training robust auditory foundation models with reduced computational costs. Code and dataset are available at https://hive-dataset-icml.github.io/Hive-Demo.