In this paper, we address a challenging task, synchronous motion captioning, that aim to generate a language description synchronized with human motion sequences. This task pertains to numerous applications, such as aligned sign language transcription and unsupervised action segmentation and temporal grounding. Our method introduces mechanisms to control self- and cross-attention distributions of the Transformer, allowing interpretability and aligned text generation. We achieve this through masking strategies and structuring losses that push the model to maximize attention only on the most important frames contributing to the generation of a motion word. These constraints aim to prevent undesired mixing of information in attention maps and to provide a monotonic attention distribution across tokens. Thus, the cross attentions of tokens are used for progressive text generation in synchronization with human motion sequences. We demonstrate the superior performance of our approach through evaluation on the two available benchmark datasets, KIT-ML and HumanML3D. As visual evaluation is essential for this task, we provide a comprehensive set of animated visual illustrations of the output of synchronous text generation in the code repository.
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Video Anomaly Understanding (VAU) is a novel task focused on describing unusual occurrences in videos. Despite growing interest, the evaluation of VAU remains an open challenge. Existing benchmarks rely on n-gram-based metrics (e.g., BLEU, ROUGE-L) or LLM-based evaluation. The first fails to capture the rich, free-form, and visually grounded nature of LVLM responses, while the latter focuses on assessing language quality over factual relevance, often resulting in subjective judgments that are misaligned with human perception. In this work, we address this issue by proposing FineVAU, a new benchmark for VAU that shifts the focus towards rich, fine-grained and domain-specific understanding of anomalous videos. We formulate VAU as a three-fold problem, with the goal of comprehensively understanding key descriptive elements of anomalies in video: events (What), participating entities (Who) and location (Where). Our benchmark introduces a) FV-Score, a novel, human-aligned evaluation metric that assesses the presence of critical visual elements in LVLM answers, providing interpretable, fine-grained feedback; and b) FineW³, a novel, comprehensive dataset curated through a structured and fully automatic procedure that augments existing human annotations with high quality, fine-grained visual information. Human evaluation reveals that our proposed metric has a superior alignment with human perception of anomalies in comparison to current approaches. Detailed experiments on FineVAU unveil critical limitations in LVLM's ability to perceive anomalous events that require spatial and fine-grained temporal understanding, despite strong performance on coarse grain, static information, and events with strong visual cues.
Suit the Remedy to the Retriever: Interpretable Query Optimization with Retriever Preference Alignment for Vision-Language Retrieval
PDF ↗Vision-language retrieval (VLR), which uses text or image queries to retrieve corresponding cross-modal content, plays a crucial role in multimedia and computer vision tasks. However, challenging concepts in queries often confuse retrievers, limiting their ability to align concepts with visual content. Existing query optimization methods neglect retrievers’ preferences (i.e., text descriptions that better match their corresponding visual content), resulting in unadapted to the retriever and leading to suboptimal performance. To address this, we propose the Retriever-Adaptive Query Optimization (RAQO), an interpretable framework that rewrites queries based on retriever-specific preferences. Specifically, we first leverages multimodal large language Models (MLLMs) and retrieval's feedback to construct the MLLMs-Driven Preference-Aware Dataset Engine (MPADE), which automatically refine queries offline, capturing the retriever’s implicit preferences. Then, we introduce a ``detect-then-rewrite" chain-of-thought rewriting (ReCoT) strategy equipped with a progressive preference alignment pipeline, including three stages: ambiguity detection fine-tuning, query rewriting fine-tuning, and preference rank optimization. This design enables the rewriter to focus on confusing concepts and produce retriever-adapted, high-quality queries. Extensive VLR benchmark experiments have demonstrated the superiority of RAQO in cross-modal retrieval, as well as its interpretability, generalizability and transferability.
Automated interpretation and reporting of chest X-rays (CXRs) hold significant promise in reducing diagnostic errors and supporting radiologists under heavy clinical workloads. However, existing methods typically rely on global visual features and token-level supervision, limiting their sensitivity to subtle abnormalities and reducing their clinical reliability. To address these challenges, we present Reflective X-ray Network (RefleXNet), which systematically integrates multi-scale visual feature fusion and anatomical relational reasoning with a targeted self-reflective learning strategy. RefleXNet first constructs multi-scale visual representations and captures anatomical context through graph-based relational modeling. Building upon these representations, we introduce a targeted self-reflection strategy that uses clinically guided feedback from generated reports to selectively refine abnormality predictions and their associated region-level visual features. Extensive experiments on MIMIC-CXR demonstrate that RefleXNet consistently outperforms state-of-the-art baselines across clinical factual correctness metrics. Notably, our compact 3B-parameter model surpasses several recent models with over twice the parameter count. Additionally, RefleXNet exhibits strong generalization performance in zero-shot evaluations on IU-Xray compared with leading multimodal language models, highlighting its robustness and clinical effectiveness.
Image-to-image translation models have achieved notable success in converting images across visual domains and are increasingly used for medical tasks such as predicting post-operative outcomes and modeling disease progression. However, most existing methods primarily aim to match the target distribution and often neglect spatial correspondences between the source and translated images. This limitation can lead to structural inconsistencies and hallucinations, undermining the reliability and interpretability of the predictions. These challenges are accentuated in clinical applications by the stringent requirement for anatomical accuracy. In this work, we present TraceTrans, a novel deformable image translation model designed for post-operative prediction that generates images aligned with the target distribution while explicitly revealing spatial correspondences with the pre-operative input. The framework employs an encoder for feature extraction and dual decoders for predicting spatial deformations and synthesizing the translated image. The predicted deformation field imposes spatial constraints on the generated output, ensuring anatomical consistency with the source. Extensive experiments on medical cosmetology and brain MRI datasets demonstrate that TraceTrans delivers accurate and interpretable post-operative predictions, highlighting its potential for reliable clinical deployment.
Visual grounding, the task of linking textual queries to specific regions within images, plays a pivotal role in vision-language integration. Existing methods typically rely on extensive task-specific annotations and fine-tuning, limiting their ability to generalize effectively to novel or out-of-distribution scenarios. To address these limitations, we introduce GroundingAgent, a novel agentic visual grounding framework that operates without any task-specific fine-tuning. GroundingAgent employs a structured, iterative reasoning mechanism that integrates pretrained open-vocabulary object detectors, multimodal large language models (MLLMs), and large language models (LLMs) to progressively refine candidate regions through joint semantic and spatial analyses. Remarkably, GroundingAgent achieves an average zero-shot grounding accuracy of 65.1% on widely-used benchmarks (RefCOCO, RefCOCO+, RefCOCOg), entirely without fine-tuning. Furthermore, by substituting MLLM-generated captions with the original query texts, the accuracy at the selection stage alone reaches approximately 90%, closely matching supervised performance and underscoring the critical role of LLM reasoning capabilities. GroundingAgent also offers strong interpretability, transparently illustrating each reasoning step, thus providing clear insights into its decision-making process.
3D visual grounding (3DVG) identifies objects in 3D scenes from language descriptions. Existing zero-shot approaches leverage 2D vision–language models (VLMs) by converting 3D spatial information (SI) into forms amenable to VLM processing, typically as composite inputs such as specified-view renderings or video sequences with overlaid object markers. However, this VLM ⊕ SI paradigm yields entangled visual representations that compel the VLM to process entire cluttered cues, making it hard to exploit spatial–semantic relationships effectively. In this work, we propose a new VLM ⊗ SI paradigm that externalizes the 3D SI into a form enabling the VLM to incrementally retrieve only what it needs during reasoning. We instantiate this paradigm with a novel View-on-Graph (VoG) method, which organizes the scene into a multi-modal, multi-layer scene graph and allows the VLM to operate as an active agent that selectively accesses necessary cues as it traverses the scene. This design offers two intrinsic advantages: (i) by structuring 3D context into a spatially and semantically coherent scene graph rather than confounding the VLM with densely entangled visual inputs, it lowers the VLM's reasoning difficulty; and (ii) by actively exploring and reasoning over the scene graph, it naturally produces transparent, step-by-step traces for interpretable 3DVG. Extensive experiments show that VoG achieves state-of-the-art zero-shot performance, establishing structured scene exploration as a promising strategy for advancing zero-shot 3DVG.
While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding. Existing alignment methods struggle to capture fine-grained correspondences between textual descriptions and visual cues across thousands of patches from a slide, compromising their performance on downstream tasks. In this paper, we propose PathFLIP (Pathology Fine-grained Language-Image Pretraining), a novel framework for holistic WSI interpretation. PathFLIP decomposes slide-level captions into region-level sub-captions and generates text-conditioned region embeddings to facilitate precise visual-language grounding. By harnessing Large Language Models (LLMs), PathFLIP can seamlessly follow diverse clinical instructions and adapt to varied diagnostic contexts. Furthermore, it exhibits versatile capabilities across multiple paradigms, efficiently handling slide-level classification and retrieval, fine-grained lesion localization, and instruction following. Extensive experiments demonstrate that PathFLIP outperforms existing large-scale pathological VLMs on four representative benchmarks while requiring significantly less training data, paving the way for fine-grained, instruction-aware WSI interpretation in research and clinical practice.
MM-R1: Unleashing the Power of Unified Multimodal Large Language Models for Personalized Image Generation
PDF ↗Multimodal Large Language Models (MLLMs) with unified architectures excel across a wide range of vision-language tasks, yet aligning them with personalized image generation remains a significant challenge. Existing methods for MLLMs are frequently subject-specific, demanding a data-intensive fine-tuning process for every new subject, which limits their scalability. In this paper, we introduce MM-R1, a framework that integrates a cross-modal Chain-of-Thought (X-CoT) reasoning strategy to unlock the inherent potential of unified MLLMs for personalized image generation. Specifically, we structure personalization as an integrated visual reasoning and generation process: (1) grounding subject concepts by interpreting and understanding user-provided images and contextual cues, and (2) generating personalized images conditioned on both the extracted subject representations and user prompts. To further enhance the reasoning capability, we adopt Grouped Reward Proximal Policy Optimization(GRPO) to explicitly align the generation. Experiments demonstrate that MM-R1 unleashes the personalization capability of unified MLLMs to generate images with high subject fidelity and strong text alignment in a zero-shot manner.
Despite the tremendous success of neural networks, benign images can be corrupted by adversarial perturbations to deceive these models. Intriguingly, images differ in their attackability. Specifically, given an attack configuration, some images are easily corrupted, whereas others are more resistant. Evaluating image attackability has important applications in active learning, adversarial training, and attack enhancement. This prompts a growing interest in developing attackability measures. However, existing methods are scarce and suffer from two major limitations: (1) They rely on a model proxy to provide prior knowledge (e.g., gradients or minimal perturbation) to extract model-dependent image features. Unfortunately, in practice, many task-specific models are not readily accessible. (2) Extracted features characterizing image attackability lack visual interpretability, obscuring their direct relationship with the images. To address these, we propose a novel Object Texture Intensity (OTI), a model-free and visually interpretable measure of image attackability, which measures image attackability as the texture intensity of the image's semantic object. Theoretically, we describe the principles of OTI from the perspectives of decision boundaries as well as the mid- and high-frequency characteristics of adversarial perturbations. Comprehensive experiments demonstrate that OTI is effective and computationally efficient. In addition, our OTI provides the adversarial machine learning community with a visual understanding of attackability.
Vector quantization has emerged as a powerful tool in large-scale multimodal models, unifying heterogeneous representations through discrete token encoding. However, its effectiveness hinges on robust codebook design. Current prototype-based approaches relying on trainable vectors or clustered centroids fall short in representativeness and interpretability, even as multimodal alignment demonstrates its promise in vision-language models. To address these limitations, we propose a simple multimodal prompting-driven quantization framework for point cloud analysis. Our methodology is built upon two core insights: 1) Text embeddings from pre-trained models inherently encode visual semantics through many-to-one contrastive alignment, naturally serving as robust prototype priors; and 2) Multimodal prompts enable adaptive refinement of these prototypes, effectively mitigating vision-language semantic gaps. The framework introduces a dual-constrained quantization space, enforced by compactness and separation regularization, which seamlessly integrates visual and prototype features, resulting in hybrid representations that jointly encode geometric and semantic information. Furthermore, we employ Gumbel-Softmax relaxation to achieve differentiable discretization while maintaining quantization sparsity. Extensive experiments on the ModelNet40 and ScanObjectNN datasets clearly demonstrate the superior effectiveness of the proposed method.
Satire, a form of artistic expression combining humor with implicit critique, holds significant social value by illuminating societal issues. Despite its cultural and societal significance, satire comprehension, particularly in purely visual forms, remains a challenging task for current vision-language models. This task requires not only detecting satire but also deciphering its nuanced meaning and identifying the implicated entities. Existing models often fail to effectively integrate local entity relationships with global context, leading to misinterpretation, comprehension biases, and hallucinations. To address these limitations, we propose SatireDecoder, a training-free framework designed to enhance satirical image comprehension. Our approach proposes a multi-agent system performing visual cascaded decoupling to decompose images into fine-grained local and global semantic representations. In addition, we introduce a chain-of-thought reasoning strategy guided by uncertainty analysis, which breaks down the complex satire comprehension process into sequential subtasks with minimized uncertainty. Our method significantly improves interpretive accuracy while reducing hallucinations. Experimental results validate that SatireDecoder outperforms existing baselines in comprehending visual satire, offering a promising direction for vision-language reasoning in nuanced, high-level semantic tasks.
From Pixels to Logic: A Perception-Reasoning Decomposition Framework for Open-World Referring Expression Comprehension
PDF ↗Recent advances in Referring Expression Comprehension (REC) have been largely driven by supervised learning on curated datasets, where each expression is assumed to refer to exactly one known object. However, such assumptions rarely hold in real-world scenarios, where expressions can refer to multiple objects, fail to refer to any, or involve novel categories and complex semantics. These challenges define the task of open-world REC, which demands robust generalization and structured reasoning beyond the scope of traditional REC methods. In this work, we introduce a novel, training-free framework that decouples visual perception from linguistic reasoning to address open-world REC. Our method first transforms the visual scene into a rich textual representation using an open-vocabulary multimodal perception module. It then employs a reasoning language model to interpret the referring expression and perform explicit logical inference over the perceived scene, enabling transparent decision-making and strong generalization in open-world scenarios. Experiments on three standard REC benchmarks as well as two more challenging ones, gRefCOCO and D³, demonstrate that our framework achieves highly competitive zero-shot performance, often surpassing supervised baselines.
While Large Vision Language Models (LVLMs) are increasingly deployed in real-world applications, their ability to interpret abstract visual inputs remains limited. Specifically, they struggle to comprehend hand-drawn sketches, a modality that offers an intuitive means of expressing concepts that are difficult to describe textually. We identify the primary bottleneck as the absence of a large-scale dataset that jointly models sketches, photorealistic images, and corresponding natural language instructions. To address this, we present two key contributions: (1) a new, large-scale dataset of image-sketch-instruction triplets designed to facilitate both pretraining and instruction tuning, and (2) O3SLM, an LVLM trained on this dataset. Comprehensive evaluations on multiple sketch-based tasks: (a) object localization, (b) counting, (c) image retrieval i.e., (SBIR and fine-grained SBIR), and (d) visual question answering (VQA); while incorporating the three existing sketch datasets, namely QuickDraw!, Sketchy, and Tu-Berlin, along with our generated SketchVCL dataset, show that O3SLM achieves state-of-the-art performance, substantially outperforming existing LVLMs in sketch comprehension and reasoning.
Concepts from Representations: Post-hoc Concept Bottleneck Models via Sparse Decomposition of Visual Representations
PDF ↗Deep learning has achieved remarkable success in image recognition, yet their inherent opacity poses challenges for deployment in critical domains. Concept-based interpretations aim to address this by explaining model reasoning through human-understandable concepts. However, existing post-hoc methods and ante-hoc concept bottleneck models (CBMs), suffer from limitations such as unreliable concept relevance, non-visual or labor-intensive concept definitions, and model/data-agnostic assumptions. This paper introduces Post-hoc Concept Bottleneck Model via Representation Decomposition (PCBM-ReD), a novel pipeline that retrofits interpretability onto pretrained opaque models. PCBM-ReD automatically extracts visual concepts from a pre-trained encoder, employs multimodal large language models (MLLMs) to label and filter concepts based on visual identifiability and task relevance, and selects an independent subset via reconstruction-guided optimization. Leveraging CLIP’s visual-text alignment, it decomposes image representations into linear combination of concept embeddings to fit into the CBMs abstraction. Extensive experiments across 11 image classification tasks show PCBM-ReD achieves state-of-the-art accuracy, narrows the performance gap with end-to-end models, and exhibits better interpretability.
BrainLMM: A Label-Free Framework for Mapping Multi-Semantic Representation in the Human Visual Cortex
PDF ↗Previous studies leveraging artificial neural networks have been used to investigate the semantic coding within human visual cortex. However, building an interpretable label-free framework that can effectively map brain responses to multiple coexisting semantic concepts remains largely unexplored. Here, we propose BrainLMM, a label-free framework for multi-semantic mapping of voxel responses by combining diverse vision encoders with the Describe-and-Dissect strategy, enabling a hypothesis-free analysis of the human high-level visual cortex. First, we construct voxel-wise encoding models leveraging diverse vision encoders to predict visual cortical responses to natural scene images. Then, we use BrainLMM to map individual brain voxels to multiple semantics without requiring any predefined labels. To evaluate the effectiveness of our method, we compute Pearson correlation coefficients to compare the multi-semantic mappings produced by BrainLMM and CLIP-MSM with ground-truth voxel responses within selective cortical areas. Our findings indicate that BrainLMM achieves more accurate predictions of visual responses compared to CLIP-MSM. Finally, to demonstrate the multi-semantic mapping capability of our method, we project multiple representative semantic concepts onto the cortical surface for visualization. Our method enables the discovery of voxels that exhibit strong activation in response to previously undefined semantic concepts across two independent datasets: the Natural Scenes Dataset (NSD) and the Natural Object Dataset (NOD).
Accurately forecasting the spatiotemporal dynamics of biological systems, such as human pluripotent stem cell (hPSC)-derived cardiac organoids, from microscopy time-series is a critical challenge in biomedicine with profound implications for drug discovery. Existing generative models often fail to capture the intricate dynamics of organoid development, struggling with their irregular morphology, indistinct boundaries, and complex spatiotemporal patterns. To overcome these limitations, we introduce OrgaCast, a novel multimodal conditional diffusion model for high-fidelity organoid forecasting. OrgaCast uniquely conditions the generative process on three synergistic modalities: (i) historical image sequences, captured by a dedicated spatiotemporal control module; (ii) structured numerical metadata defining experimental conditions; and (iii) descriptive text captions summarizing the biological context. This comprehensive conditioning enables the generation of forecasts with high visual accuracy and biological plausibility. Furthermore, to enhance the model's utility in critical research settings, we introduce a post-hoc uncertainty quantification method that produces intuitive confidence maps, bolstering the interpretability and trustworthiness of predictions. Extensive experiments on a challenging cardiac organoid dataset demonstrate that OrgaCast outperforms baselines in metrics such as SSIM, PSNR, and LPIPS. Our framework presents a robust solution for biological forecasting, promising to accelerate research discovery while minimizing experimental costs and manual effort.
Rethinking Saliency Maps: A Cognitive Human Aligned Taxonomy and Evaluation Framework for Explanations
PDF ↗Saliency maps have become a cornerstone of visual explanation in deep learning, yet there remains no consensus on their intended purpose and their alignment with specific user queries. This fundamental ambiguity undermines both the evaluation and practical utility of explanation methods. In this paper, we introduce the Reference-Frame x Granularity (RFxG) taxonomy—a principled framework that addresses this ambiguity by conceptualizing saliency explanations along two essential axes: the reference-frame axis (distinguishing between pointwise "Why Husky?" and contrastive "Why Husky and not Shih-tzu?" explanations) and the granularity axis (ranging from fine-grained class-level to coarse-grained group-level interpretations, e.g., “Why Husky?” vs. “Why Dog?”). Through this lens, we identify critical limitations in existing evaluation metrics, which predominantly focus on pointwise faithfulness while neglecting contrastive reasoning and semantic granularity. To address these gaps, we propose four novel faithfulness metrics that systematically assess explanation quality across both RFxG dimensions. Our comprehensive evaluation framework spans ten state-of-the-art methods, 4 model architectures, and 3 datasets. By suggesting a shift from model-centric to user-intent-driven evaluation, our work provides both the conceptual foundation and practical tools necessary for developing explanations that are not only faithful to model behavior but also meaningfully aligned with human understanding.
Large-scale vision-language models (VLMs) embedded with expansive representations and visual concepts have showcased significant potential in image and text understanding. Efficiently adapting VLMs such as CLIP to downstream tasks like few-shot image classification has garnered growing attention, with prompt learning emerging as a representative approach. However, most existing prompt-based adaptation methods, which rely solely on coarse-grained textual prompts, suffer from limited performance and interpretability when handling domain tasks that require specific knowledge. This results in a failure to satisfy the stringent trustworthiness requirements of Explainable Artificial Intelligence (XAI) in high-risk scenarios like healthcare. To address this issue, we propose a Knowledge-Enhanced Explainable Prompting (KEEP) framework that leverages fine-grained domain-specific knowledge to enhance the adaptation process of VLMs across various domains and image modalities. By incorporating retrieval augmented generation and domain foundation models, our framework can provide more reliable image-wise knowledge for prompt learning in various domains, alleviating the lack of fine-grained annotations, while offering both visual and textual explanations. Extensive experiments and explainability analyses conducted on eight datasets of different domains and image modalities demonstrate that our method simultaneously achieves superior performance and interpretability, highlighting the effectiveness of the collaboration between foundation models and XAI.
The primate visual cortex exhibits topographic organization, where functionally similar neurons are spatially clustered, a structure widely believed to enhance neural processing efficiency. While prior works have demonstrated that conventional deep ANNs can develop topographic representations, these models largely neglect crucial temporal dynamics. This oversight often leads to significant performance degradation in tasks like object recognition and compromises their biological fidelity. To address this, we leverage spiking neural networks (SNNs), which inherently capture spike-based temporal dynamics and offer enhanced biological plausibility. We propose a novel Spatio-Temporal Constraints (STC) loss function for topographic deep spiking neural networks (TDSNNs), successfully replicating the hierarchical spatial functional organization observed in the primate visual cortex from low-level sensory input to high-level abstract representations. Our results show that STC effectively generates representative topographic features across simulated visual cortical areas. While introducing topography typically leads to significant performance degradation in ANNs, our spiking architecture exhibits a remarkably small performance drop (No drop in ImageNet top-1 accuracy, compared to a 3% drop observed in TopoNet, which is the best-performing topographic ANN so far) and outperforms topographic ANNs in brain-likeness. We also reveal that topographic organization facilitates efficient and stable temporal information processing via the spike mechanism in TDSNNs, contributing to model robustness. These findings suggest that TDSNNs offer a compelling balance between computational performance and brain-like features, providing not only a framework for interpreting neural science phenomena but also novel insights for designing more efficient and robust deep learning models.